4LLM

Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 1, CRD1) at 1.75A

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0002250	biological_process	adaptive immune response
B	0002376	biological_process	immune system process
B	0003823	molecular_function	antigen binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005886	cellular_component	plasma membrane
B	0016020	cellular_component	membrane
B	0016064	biological_process	immunoglobulin mediated immune response
B	0019814	cellular_component	immunoglobulin complex
B	0070062	cellular_component	extracellular exosome
B	0071735	cellular_component	IgG immunoglobulin complex
B	0072562	cellular_component	blood microparticle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
A	TYR213-HIS219
B	TYR195-HIS201

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	93
Details	Domain: {"description":"Ig-like 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	97
Details	Region: {"description":"CH1"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	20
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	94
Details	Domain: {"description":"Ig-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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