4LDZ
Crystal structure of the full-length response regulator DesR in the active state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000160 | biological_process | phosphorelay signal transduction system |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0000160 | biological_process | phosphorelay signal transduction system |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 201 |
| Chain | Residue |
| A | ASP9 |
| A | ASP54 |
| A | GLU56 |
| A | BEF202 |
| A | HOH302 |
| A | HOH303 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE BEF A 202 |
| Chain | Residue |
| A | THR80 |
| A | THR81 |
| A | PHE82 |
| A | LYS102 |
| A | MG201 |
| A | GOL203 |
| A | HOH302 |
| A | ASP54 |
| A | ILE55 |
| A | GLU56 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 203 |
| Chain | Residue |
| A | GLN10 |
| A | THR81 |
| A | PHE82 |
| A | LYS102 |
| A | BEF202 |
| A | HOH303 |
| B | GLN10 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 204 |
| Chain | Residue |
| A | SER19 |
| A | ASN22 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 205 |
| Chain | Residue |
| A | ASN22 |
| A | GLU24 |
| A | MET27 |
| A | HOH313 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 201 |
| Chain | Residue |
| B | ASP9 |
| B | ASP54 |
| B | GLU56 |
| B | BEF202 |
| B | HOH301 |
| B | HOH302 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE BEF B 202 |
| Chain | Residue |
| B | ASP54 |
| B | ILE55 |
| B | GLU56 |
| B | THR80 |
| B | THR81 |
| B | PHE82 |
| B | LYS102 |
| B | MG201 |
| B | HOH301 |
| B | HOH302 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 203 |
| Chain | Residue |
| B | ASN22 |
| B | GLU24 |
| B | MET27 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 228 |
| Details | Domain: {"description":"Response regulatory","evidences":[{"source":"PROSITE-ProRule","id":"PRU00169","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00411","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"4-aspartylphosphate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00169","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
