4LDS
The inward-facing structure of the glucose transporter from Staphylococcus epidermidis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005355 | molecular_function | glucose transmembrane transporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0015293 | molecular_function | symporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0071702 | biological_process | organic substance transport |
| A | 1904659 | biological_process | glucose transmembrane transport |
| B | 0005355 | molecular_function | glucose transmembrane transporter activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0015293 | molecular_function | symporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0071702 | biological_process | organic substance transport |
| B | 1904659 | biological_process | glucose transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00216 |
| Number of Residues | 18 |
| Details | SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. SGPLADKLGRRrlvmliA |
| Chain | Residue | Details |
| A | SER62-ALA79 |
| site_id | PS00217 |
| Number of Residues | 26 |
| Details | SUGAR_TRANSPORT_2 Sugar transport proteins signature 2. IiGLAvGGsmstvpvYlsEmapteyR |
| Chain | Residue | Details |
| A | ILE104-ARG129 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 214 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:24127585 |
| Chain | Residue | Details |
| A | MET1-TYR6 | |
| A | LEU65-GLY70 | |
| A | MET123-ARG129 | |
| A | MET181-PRO234 | |
| A | PHE296-ARG303 | |
| A | PHE364-GLY370 | |
| A | PHE421-GLU446 | |
| B | MET1-TYR6 | |
| B | LEU65-GLY70 | |
| B | MET123-ARG129 | |
| B | MET181-PRO234 | |
| B | PHE296-ARG303 | |
| B | PHE364-GLY370 | |
| B | PHE421-GLU446 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 594 |
| Details | TRANSMEM: Helical => ECO:0000305|PubMed:24127585 |
| Chain | Residue | Details |
| A | LEU7-LEU31 | |
| A | LEU39-PRO64 | |
| A | ARG71-ALA90 | |
| A | LEU95-GLU122 | |
| A | GLY130-TYR152 | |
| A | ALA155-PHE180 | |
| A | TRP235-ALA269 | |
| A | GLU273-ILE295 | |
| A | LYS304-LEU324 | |
| A | ILE330-LEU363 | |
| A | ALA371-SER399 | |
| A | TRP402-LYS420 | |
| B | LEU7-LEU31 | |
| B | LEU39-PRO64 | |
| B | ARG71-ALA90 | |
| B | LEU95-GLU122 | |
| B | GLY130-TYR152 | |
| B | ALA155-PHE180 | |
| B | TRP235-ALA269 | |
| B | GLU273-ILE295 | |
| B | LYS304-LEU324 | |
| B | ILE330-LEU363 | |
| B | ALA371-SER399 | |
| B | TRP402-LYS420 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | TOPO_DOM: Extracellular => ECO:0000305|PubMed:24127585 |
| Chain | Residue | Details |
| A | PHE32-PRO38 | |
| A | ALA91-ASN94 | |
| A | ALA153-PHE154 | |
| A | GLY270-GLY272 | |
| A | ILE325-GLY329 | |
| A | THR400-GLU401 | |
| B | PHE32-PRO38 | |
| B | ALA91-ASN94 | |
| B | ALA153-PHE154 | |
| B | GLY270-GLY272 | |
| B | ILE325-GLY329 | |
| B | THR400-GLU401 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Important for symport activity => ECO:0000305|PubMed:24127585 |
| Chain | Residue | Details |
| A | ASP22 | |
| A | ILE105 | |
| B | ASP22 | |
| B | ILE105 |
