4LD5

Crystal structure of MepR Q18P mutant from multidrug resistant S. aureus clinical isolate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006950	biological_process	response to stress
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006950	biological_process	response to stress
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006950	biological_process	response to stress
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0006355	biological_process	regulation of DNA-templated transcription
D	0006950	biological_process	response to stress
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0006355	biological_process	regulation of DNA-templated transcription
E	0006950	biological_process	response to stress
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0006355	biological_process	regulation of DNA-templated transcription
F	0006950	biological_process	response to stress
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006355	biological_process	regulation of DNA-templated transcription
G	0006950	biological_process	response to stress
H	0003700	molecular_function	DNA-binding transcription factor activity
H	0006355	biological_process	regulation of DNA-templated transcription
H	0006950	biological_process	response to stress

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 201

Chain	Residue
A	TYR80
A	VAL81
F	LYS23
F	GLN26
F	ARG87

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 201

Chain	Residue
E	LYS89
E	GLN50
E	SER65
E	ARG69
E	ARG79

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 F 201

Chain	Residue
E	LEU24
E	THR30
E	ASN31
F	ARG10
F	HOH310

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 201

Chain	Residue
H	THR49
H	ASN51
H	ARG88
H	HOH330

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 H 202

Chain	Residue
H	ARG59
H	THR60
H	THR63

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site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 203

Chain	Residue
H	GLN50
H	SER65
H	ARG69
H	ARG79
H	LYS89

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site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 H 204

Chain	Residue
C	TYR80
C	VAL81
H	LYS23
H	GLN26
H	ARG87
H	HOH318

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