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4LBQ

Crystal structure of mouse galectin-1

Functional Information from GO Data
ChainGOidnamespacecontents
A0002317biological_processplasma cell differentiation
A0005515molecular_functionprotein binding
A0005534molecular_functiongalactose binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006915biological_processapoptotic process
A0007157biological_processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
A0007165biological_processsignal transduction
A0030246molecular_functioncarbohydrate binding
A0031295biological_processT cell costimulation
A0043065biological_processpositive regulation of apoptotic process
A0045185biological_processmaintenance of protein location
A0045445biological_processmyoblast differentiation
A0046598biological_processpositive regulation of viral entry into host cell
A0048018molecular_functionreceptor ligand activity
A0050729biological_processpositive regulation of inflammatory response
A0062023cellular_componentcollagen-containing extracellular matrix
A0098609biological_processcell-cell adhesion
A1990724cellular_componentgalectin complex
A2000329biological_processnegative regulation of T-helper 17 cell lineage commitment
B0002317biological_processplasma cell differentiation
B0005515molecular_functionprotein binding
B0005534molecular_functiongalactose binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006915biological_processapoptotic process
B0007157biological_processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
B0007165biological_processsignal transduction
B0030246molecular_functioncarbohydrate binding
B0031295biological_processT cell costimulation
B0043065biological_processpositive regulation of apoptotic process
B0045185biological_processmaintenance of protein location
B0045445biological_processmyoblast differentiation
B0046598biological_processpositive regulation of viral entry into host cell
B0048018molecular_functionreceptor ligand activity
B0050729biological_processpositive regulation of inflammatory response
B0062023cellular_componentcollagen-containing extracellular matrix
B0098609biological_processcell-cell adhesion
B1990724cellular_componentgalectin complex
B2000329biological_processnegative regulation of T-helper 17 cell lineage commitment
C0002317biological_processplasma cell differentiation
C0005515molecular_functionprotein binding
C0005534molecular_functiongalactose binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0006915biological_processapoptotic process
C0007157biological_processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
C0007165biological_processsignal transduction
C0030246molecular_functioncarbohydrate binding
C0031295biological_processT cell costimulation
C0043065biological_processpositive regulation of apoptotic process
C0045185biological_processmaintenance of protein location
C0045445biological_processmyoblast differentiation
C0046598biological_processpositive regulation of viral entry into host cell
C0048018molecular_functionreceptor ligand activity
C0050729biological_processpositive regulation of inflammatory response
C0062023cellular_componentcollagen-containing extracellular matrix
C0098609biological_processcell-cell adhesion
C1990724cellular_componentgalectin complex
C2000329biological_processnegative regulation of T-helper 17 cell lineage commitment
D0002317biological_processplasma cell differentiation
D0005515molecular_functionprotein binding
D0005534molecular_functiongalactose binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006915biological_processapoptotic process
D0007157biological_processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
D0007165biological_processsignal transduction
D0030246molecular_functioncarbohydrate binding
D0031295biological_processT cell costimulation
D0043065biological_processpositive regulation of apoptotic process
D0045185biological_processmaintenance of protein location
D0045445biological_processmyoblast differentiation
D0046598biological_processpositive regulation of viral entry into host cell
D0048018molecular_functionreceptor ligand activity
D0050729biological_processpositive regulation of inflammatory response
D0062023cellular_componentcollagen-containing extracellular matrix
D0098609biological_processcell-cell adhesion
D1990724cellular_componentgalectin complex
D2000329biological_processnegative regulation of T-helper 17 cell lineage commitment
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL A 201
ChainResidue
AASN62
ATRP69
AGLU72

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE GOL B 201
ChainResidue
BHIS73
BPRO110
BARG112
CARG74

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE GOL C 201
ChainResidue
CASN62
CGLU72
CHIS45
CARG49

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE GOL D 201
ChainResidue
AHIS53
DASN62
DTRP69
DGLU72

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
DHIS45
DHIS53
DASN62
DTRP69
CHIS45
CHIS53
CASN62
CTRP69

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P09382
ChainResidueDetails
DALA2
CALA2

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23806337
ChainResidueDetails
DLYS13
DLYS19
DLYS29
DLYS128
CLYS13
CLYS19
CLYS29
CLYS128

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P09382
ChainResidueDetails
DSER30
CSER30

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0007744|PubMed:23806337
ChainResidueDetails
DLYS108
CLYS108

226707

PDB entries from 2024-10-30

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