4L9Y

Crystal Structure of Rhodobacter sphaeroides malyl-CoA lyase in complex with magnesium, glyoxylate, and propionyl-CoA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0006107	biological_process	oxaloacetate metabolic process
A	0043959	molecular_function	L-erythro-3-methylmalyl-CoA lyase activity
A	0046872	molecular_function	metal ion binding
A	0047777	molecular_function	(S)-citramalyl-CoA lyase activity
A	0050083	molecular_function	malyl-CoA lyase activity
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0006107	biological_process	oxaloacetate metabolic process
B	0043959	molecular_function	L-erythro-3-methylmalyl-CoA lyase activity
B	0046872	molecular_function	metal ion binding
B	0047777	molecular_function	(S)-citramalyl-CoA lyase activity
B	0050083	molecular_function	malyl-CoA lyase activity
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0006107	biological_process	oxaloacetate metabolic process
C	0043959	molecular_function	L-erythro-3-methylmalyl-CoA lyase activity
C	0046872	molecular_function	metal ion binding
C	0047777	molecular_function	(S)-citramalyl-CoA lyase activity
C	0050083	molecular_function	malyl-CoA lyase activity
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0006107	biological_process	oxaloacetate metabolic process
D	0043959	molecular_function	L-erythro-3-methylmalyl-CoA lyase activity
D	0046872	molecular_function	metal ion binding
D	0047777	molecular_function	(S)-citramalyl-CoA lyase activity
D	0050083	molecular_function	malyl-CoA lyase activity
E	0000287	molecular_function	magnesium ion binding
E	0003824	molecular_function	catalytic activity
E	0006107	biological_process	oxaloacetate metabolic process
E	0043959	molecular_function	L-erythro-3-methylmalyl-CoA lyase activity
E	0046872	molecular_function	metal ion binding
E	0047777	molecular_function	(S)-citramalyl-CoA lyase activity
E	0050083	molecular_function	malyl-CoA lyase activity
F	0000287	molecular_function	magnesium ion binding
F	0003824	molecular_function	catalytic activity
F	0006107	biological_process	oxaloacetate metabolic process
F	0043959	molecular_function	L-erythro-3-methylmalyl-CoA lyase activity
F	0046872	molecular_function	metal ion binding
F	0047777	molecular_function	(S)-citramalyl-CoA lyase activity
F	0050083	molecular_function	malyl-CoA lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 401

Chain	Residue
A	GLU141
A	ASP168
A	HOH501
A	HOH519
A	HOH546
A	HOH602

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 402

Chain	Residue
A	ASP168
A	HOH501
A	GLY165
A	ALA166
A	ALA167

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE 1VU B 401

Chain	Residue
A	ASP299
B	PHE19
B	GLY20
B	ARG24
B	LYS30
B	MET31
B	ARG76
B	ALA167
B	ILE180
B	ILE251
B	HIS252
B	PRO253
B	GLV402
B	HOH510
B	HOH661
B	HOH691

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GLV B 402

Chain	Residue
B	ARG76
B	GLU141
B	GLY165
B	ALA166
B	ALA167
B	ASP168
B	PRO223
B	1VU401
B	MG403
B	HOH510

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 403

Chain	Residue
B	ASP45
B	GLU141
B	ASP168
B	GLV402
B	HOH510
B	HOH724

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG C 401

Chain	Residue
C	ASP45
C	GLU141
C	ASP168
C	HOH502
C	HOH503
C	HOH507
C	HOH763

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL C 402

Chain	Residue
C	GLY165
C	ALA166
C	ALA167
C	ASP168
C	HOH502
C	HOH627

---

site_id	AC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GLV D 401

Chain	Residue
D	ARG76
D	GLU141
D	GLY165
D	ALA166
D	ALA167
D	ASP168
D	PRO223
D	TRP249
D	MG402
D	HOH501

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 402

Chain	Residue
D	GLU141
D	ASP168
D	GLV401
D	HOH501
D	HOH733

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG E 401

Chain	Residue
E	ASP45
E	GLU141
E	ASP168
E	HOH501
E	HOH513
E	HOH724
E	HOH757

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL E 402

Chain	Residue
E	GLY165
E	ALA166
E	ALA167
E	ASP168
E	PRO223
E	HOH724

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG F 401

Chain	Residue
F	ASP45
F	GLU141
F	ASP168
F	HOH503
F	HOH506
F	HOH526
F	HOH747

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL F 402

Chain	Residue
F	GLY165
F	ALA166
F	ALA167
F	ASP168
F	PRO223
F	HOH747

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24206647","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4L9Y","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24206647","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4L9Z","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24206647","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4L9Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4L9Z","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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