4L35

Crystal structure of cruxrhodopsin-3 at pH5 from Haloarcula vallismortis at 2.1 angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0007602	biological_process	phototransduction
A	0009881	molecular_function	photoreceptor activity
A	0016020	cellular_component	membrane
A	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE RET A 301

Chain	Residue
A	TYR81
A	TRP186
A	TYR189
A	PRO190
A	TRP193
A	LYS220
A	TRP84
A	THR87
A	THR88
A	LEU91
A	MET116
A	TRP142
A	SER145
A	THR146

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 22B A 302

Chain	Residue
A	GLY29
A	TRP30
A	TYR41
A	PHE52
A	ASN104
A	THR105
A	LEU112
A	PHE148
A	SER159

---

Functional Information from PROSITE/UniProt

site_id	PS00327
Number of Residues	12
Details	BACTERIAL_OPSIN_RET Bacterial rhodopsins retinal binding site. FMVIDLvAKvGF

Chain	Residue	Details
A	PHE212-PHE223

---

site_id	PS00950
Number of Residues	13
Details	BACTERIAL_OPSIN_1 Bacterial rhodopsins signature 1. RYsDWlFTTPLLL

Chain	Residue	Details
A	ARG80-LEU92

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	47
Details	TOPO_DOM: Extracellular => ECO:0000269|PubMed:25268964

Chain	Residue	Details
A	MET1-ILE9
A	GLY61-TYR77
A	SER126-ARG138
A	GLY196-ILE207

---

site_id	SWS_FT_FI2
Number of Residues	17
Details	TRANSMEM: Helical; Name=Helix A => ECO:0000269|PubMed:25268964

Chain	Residue	Details
A	TRP10-ALA27

---

site_id	SWS_FT_FI3
Number of Residues	62
Details	TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:25268964

Chain	Residue	Details
A	ARG28-TYR41
A	LEU95-THR105
A	SER159-LYS176
A	LEU228-ASP250

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	TRANSMEM: Helical; Name=Helix B => ECO:0000269|PubMed:25268964

Chain	Residue	Details
A	ILE42-LEU60

---

site_id	SWS_FT_FI5
Number of Residues	16
Details	TRANSMEM: Helical; Name=Helix C => ECO:0000269|PubMed:25268964

Chain	Residue	Details
A	TRP78-ASP94

---

site_id	SWS_FT_FI6
Number of Residues	19
Details	TRANSMEM: Helical; Name=Helix D => ECO:0000269|PubMed:25268964

Chain	Residue	Details
A	ILE106-LEU125

---

site_id	SWS_FT_FI7
Number of Residues	19
Details	TRANSMEM: Helical; Name=Helix E => ECO:0000269|PubMed:25268964

Chain	Residue	Details
A	LEU139-SER158

---

site_id	SWS_FT_FI8
Number of Residues	18
Details	TRANSMEM: Helical; Name=Helix F => ECO:0000269|PubMed:25268964

Chain	Residue	Details
A	THR177-VAL195

---

site_id	SWS_FT_FI9
Number of Residues	19
Details	TRANSMEM: Helical; Name=Helix G => ECO:0000269|PubMed:25268964

Chain	Residue	Details
A	GLU208-LEU227

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	SITE: Primary proton acceptor => ECO:0000250|UniProtKB:P02945

Chain	Residue	Details
A	ASP83

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: N6-(retinylidene)lysine => ECO:0000269|PubMed:25268964, ECO:0007744|PDB:4JR8, ECO:0007744|PDB:4L35

Chain	Residue	Details
A	LYS220

---