4L2H
Structure of a catalytically inactive PARG in complex with a poly-ADP-ribose fragment
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004649 | molecular_function | poly(ADP-ribose) glycohydrolase activity |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0005975 | biological_process | carbohydrate metabolic process |
A | 0006282 | biological_process | regulation of DNA repair |
A | 0009225 | biological_process | nucleotide-sugar metabolic process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0140292 | molecular_function | ADP-ribosylserine hydrolase activity |
A | 1990966 | biological_process | ATP generation from poly-ADP-D-ribose |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 38 |
Details | BINDING SITE FOR LINKED RESIDUES A 700 to 701 |
Chain | Residue |
A | ARG164 |
A | ASN250 |
A | GLY251 |
A | LEU252 |
A | VAL253 |
A | GLN254 |
A | GLU255 |
A | GLN256 |
A | TYR296 |
A | SER297 |
A | LYS365 |
A | LEU226 |
A | GLY367 |
A | CYS368 |
A | GLY369 |
A | ALA370 |
A | PHE371 |
A | PHE398 |
A | HOH815 |
A | HOH825 |
A | HOH827 |
A | HOH835 |
A | ILE227 |
A | HOH888 |
A | HOH930 |
A | HOH1048 |
A | HOH1051 |
A | HOH1075 |
A | HOH1120 |
A | HOH1143 |
A | HOH1149 |
A | HOH1259 |
A | GLU228 |
A | PHE238 |
A | ASN240 |
A | GLY245 |
A | GLY246 |
A | GLY249 |