4KU2
Crystal Structure C143A from Xanthomonas campestris Bound with Myristoyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0044550 | biological_process | secondary metabolite biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE MYA B 401 |
| Chain | Residue |
| B | THR60 |
| B | ARG251 |
| B | LEU253 |
| B | ILE258 |
| B | HIS285 |
| B | VAL287 |
| B | SER288 |
| B | HIS291 |
| B | ASN315 |
| B | LEU343 |
| B | ILE345 |
| B | VAL62 |
| B | SER347 |
| B | MET353 |
| B | HOH509 |
| B | HOH576 |
| B | HOH694 |
| B | HOH697 |
| B | VAL66 |
| B | ALA67 |
| B | PHE194 |
| B | ARG195 |
| B | LEU198 |
| B | THR202 |
| B | THR250 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:22524624, ECO:0000305|PubMed:27815501, ECO:0000305|PubMed:29025976 |
| Chain | Residue | Details |
| A | GLU117 | |
| B | GLU117 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Acyl-thioester intermediate => ECO:0000305|PubMed:22524624, ECO:0000305|PubMed:27815501, ECO:0000305|PubMed:29025976 |
| Chain | Residue | Details |
| A | ALA143 | |
| B | ALA143 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22524624, ECO:0000269|PubMed:29025976, ECO:0000269|Ref.7 |
| Chain | Residue | Details |
| A | HIS38 | |
| A | ASP76 | |
| B | HIS38 | |
| B | ASP76 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Important for activity => ECO:0000305|PubMed:29430657 |
| Chain | Residue | Details |
| A | HIS285 | |
| B | HIS285 |
