4KTN

Dna gyrase atp binding domain of enterococcus faecalis in complex with a small molecule inhibitor ((3S)-1-[2-(PYRIDO[2,3-B]PYRAZIN-7-YLSULFANYL)-9H-PYRIMIDO[4,5-B]INDOL-4-YL]PYRROLIDIN-3-AMINE)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE MJU A 301

Chain	Residue
A	ILE45
A	SER122
A	THR167
A	HOH428
A	HOH530
A	HOH534
A	HOH631
A	HOH645
A	ASN48
A	SER49
A	GLU52
A	ASP75
A	ARG78
A	GLY79
A	ILE80
A	PRO81

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