4KSI

Crystal Structure Analysis of the Acidic Leucine Aminopeptidase of Tomato

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004177	molecular_function	aminopeptidase activity
A	0005737	cellular_component	cytoplasm
A	0006457	biological_process	protein folding
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0009507	cellular_component	chloroplast
A	0009611	biological_process	response to wounding
A	0009617	biological_process	response to bacterium
A	0009625	biological_process	response to insect
A	0009753	biological_process	response to jasmonic acid
A	0016787	molecular_function	hydrolase activity
A	0019538	biological_process	protein metabolic process
A	0030145	molecular_function	manganese ion binding
A	0034214	biological_process	protein hexamerization
A	0034605	biological_process	cellular response to heat
A	0042802	molecular_function	identical protein binding
A	0043171	biological_process	peptide catabolic process
A	0044183	molecular_function	protein folding chaperone
A	0046872	molecular_function	metal ion binding
A	0070006	molecular_function	metalloaminopeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 601

Chain	Residue
A	ASP347
A	ASP427
A	GLU429
A	MG602
A	SO4603
A	HOH701

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 602

Chain	Residue
A	GLU429
A	MG601
A	SO4603
A	HOH701
A	HOH944
A	LYS342
A	ASP347
A	ASP367

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 A 603

Chain	Residue
A	LYS342
A	ASP427
A	ALA428
A	GLU429
A	GLY430
A	ARG431
A	LEU455
A	MG601
A	MG602
A	HOH701

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 606

Chain	Residue
A	GLY145

---

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 607

Chain	Residue
A	TRP84
A	GLN85
A	GLY86
A	ASP87
A	LEU88
A	GLY145
A	GLY146
A	ARG147
A	HOH1001

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 608

Chain	Residue
A	SER290
A	ASN292
A	HIS323
A	CYS325
A	HOH1086

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 609

Chain	Residue
A	ASN474
A	ASP475
A	ASP476
A	LEU477
A	GLN538
A	HOH869

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 610

Chain	Residue
A	ASN424
A	ASN425
A	HOH1149

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 611

Chain	Residue
A	PRO70
A	LYS71
A	ILE72
A	GLU249
A	HOH1091
A	HOH1157

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IMD A 612

Chain	Residue
A	TRP502
A	MET505
A	LYS506
A	ASP511
A	HOH1034

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MPD A 613

Chain	Residue
A	HIS164
A	ASN199
A	SER202
A	THR206
A	SER488

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 614

Chain	Residue
A	ALA272
A	GLU276
A	LYS279
A	TYR320

---

Functional Information from PROSITE/UniProt

site_id	PS00631
Number of Residues	8
Details	CYTOSOL_AP Cytosol aminopeptidase signature. NTDAEGRL

Chain	Residue	Details
A	ASN425-LEU432

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24914976","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4KSI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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