4KSH

Dna gyrase atp binding domain of enterococcus faecalis in complex with a small molecule inhibitor (7-({4-[(3R)-3-AMINOPYRROLIDIN-1-YL]-5-CHLORO-6-ETHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-2-YL}SULFANYL)-1,5-NAPHTHYRIDIN-1(4H)-OL)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HTT A 301

Chain	Residue
A	ASN48
A	LYS138
A	THR167
A	HOH407
A	HOH435
A	HOH519
A	SER49
A	GLU52
A	ASP75
A	ARG78
A	GLY79
A	ILE80
A	GLY119
A	SER122

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 302

Chain	Residue
A	ALA53
A	THR130
A	ARG148
A	ARG149
A	ASN200
A	ARG201
A	LEU203
A	HOH472
A	HOH617

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