4KSG
Dna gyrase atp binding domain of enterococcus faecalis in complex with a small molecule inhibitor (4-[(1S,5R,6R)-6-AMINO-1-METHYL-3-AZABICYCLO[3.2.0]HEPT-3-YL]-6-FLUORO-N-METHYL-2-[(2-METHYLPYRIMIDIN-5-YL)OXY]-9H-PYRIMIDO[4,5-B]INDOL-8-AMINE)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 920 A 301 |
| Chain | Residue |
| A | ASN48 |
| A | PHE97 |
| A | SER122 |
| A | THR167 |
| A | VAL169 |
| A | HOH410 |
| A | HOH419 |
| A | HOH475 |
| A | HOH528 |
| A | HOH553 |
| A | SER49 |
| A | GLU52 |
| A | VAL73 |
| A | ASP75 |
| A | ARG78 |
| A | GLY79 |
| A | ILE80 |
| A | PRO81 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE TBU A 302 |
| Chain | Residue |
| A | ALA53 |
| A | THR130 |
| A | ARG148 |
| A | ASN200 |
| A | ARG201 |
