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4KS5

Influenza neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid

Functional Information from GO Data
ChainGOidnamespacecontents
A0004308molecular_functionexo-alpha-sialidase activity
A0005975biological_processcarbohydrate metabolic process
A0016020cellular_componentmembrane
A0033644cellular_componenthost cell membrane
A0055036cellular_componentvirion membrane
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA A 501
ChainResidue
AASP293
AGLY297
AASP324
ATYR347
AGLY348
AHOH640

site_idAC2
Number of Residues12
DetailsBINDING SITE FOR RESIDUE 1SO A 502
ChainResidue
AARG152
AARG156
ATRP178
AARG224
AGLU276
AGLU277
AARG292
AARG371
ATYR406
AGLU119
ALEU134
AASP151

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PDB entries from 2025-07-30

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