4KP1
Crystal structure of IPM isomerase large subunit from methanococcus jannaschii (MJ0499)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003861 | molecular_function | 3-isopropylmalate dehydratase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016836 | molecular_function | hydro-lyase activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047508 | molecular_function | (R)-2-methylmalate dehydratase activity |
| A | 0050075 | molecular_function | maleate hydratase activity |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE KP1 A 501 |
| Chain | Residue |
| A | PHE300 |
| A | SER303 |
| A | SER384 |
| A | HOH797 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE MPD A 502 |
| Chain | Residue |
| A | ASN389 |
| A | PHE390 |
| A | GLN394 |
| A | ILE401 |
| A | HOH728 |
| A | ALA277 |
| A | CYS278 |
| A | HIS280 |
| A | ASN281 |
| A | VAL282 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 503 |
| Chain | Residue |
| A | GLU257 |
| A | VAL264 |
| A | GLU320 |
| A | LYS321 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MPD A 504 |
| Chain | Residue |
| A | TYR49 |
| A | HIS145 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MPD A 505 |
| Chain | Residue |
| A | GLY198 |
| A | GLY199 |
| A | LYS203 |
| A | ARG210 |
| A | GLU228 |
| A | ASP230 |
| A | LYS321 |
| A | GLY323 |
| A | HOH683 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 506 |
| Chain | Residue |
| A | HIS103 |
| A | ASN215 |
| A | CYS304 |
| A | THR305 |
| A | ARG388 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01027","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
