4KNW
The crystal structure of human HDHD4 IN COMPLEX WITH MAGNESIUM AND THE PHOSPHATE MIMETIC VANADATE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005575 | cellular_component | cellular_component |
| A | 0005829 | cellular_component | cytosol |
| A | 0006045 | biological_process | N-acetylglucosamine biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016791 | molecular_function | phosphatase activity |
| A | 0044283 | biological_process | small molecule biosynthetic process |
| A | 0046380 | biological_process | N-acetylneuraminate biosynthetic process |
| A | 0050124 | molecular_function | N-acylneuraminate-9-phosphatase activity |
| B | 0005575 | cellular_component | cellular_component |
| B | 0005829 | cellular_component | cytosol |
| B | 0006045 | biological_process | N-acetylglucosamine biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016791 | molecular_function | phosphatase activity |
| B | 0044283 | biological_process | small molecule biosynthetic process |
| B | 0046380 | biological_process | N-acetylneuraminate biosynthetic process |
| B | 0050124 | molecular_function | N-acylneuraminate-9-phosphatase activity |
| C | 0005575 | cellular_component | cellular_component |
| C | 0005829 | cellular_component | cytosol |
| C | 0006045 | biological_process | N-acetylglucosamine biosynthetic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016791 | molecular_function | phosphatase activity |
| C | 0044283 | biological_process | small molecule biosynthetic process |
| C | 0046380 | biological_process | N-acetylneuraminate biosynthetic process |
| C | 0050124 | molecular_function | N-acylneuraminate-9-phosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE VO4 A 301 |
| Chain | Residue |
| A | ASP14 |
| A | LEU15 |
| A | ASP16 |
| A | THR133 |
| A | ASN134 |
| A | LYS166 |
| A | MG302 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 302 |
| Chain | Residue |
| A | ASP191 |
| A | VO4301 |
| A | ASP14 |
| A | ASP16 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE VO4 B 301 |
| Chain | Residue |
| B | ASP14 |
| B | LEU15 |
| B | ASP16 |
| B | THR133 |
| B | ASN134 |
| B | LYS166 |
| B | ASP196 |
| B | MG302 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 302 |
| Chain | Residue |
| B | ASP14 |
| B | ASP16 |
| B | ASP191 |
| B | THR192 |
| B | VO4301 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE VO4 C 301 |
| Chain | Residue |
| C | ASP14 |
| C | LEU15 |
| C | ASP16 |
| C | THR133 |
| C | ASN134 |
| C | LYS166 |
| C | ASP196 |
| C | MG302 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 302 |
| Chain | Residue |
| C | ASP14 |
| C | ASP16 |
| C | ASP191 |
| C | VO4301 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP14 | |
| A | THR133 | |
| A | LYS166 | |
| B | ASP14 | |
| B | THR133 | |
| B | LYS166 | |
| C | ASP14 | |
| C | THR133 | |
| C | LYS166 |
