4KLZ
Inhibition of Small GTPases by Stabilization of the GDP Complex, a Novel Approach applied to Rit1, a Target for Rheumatoid Arthritis
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GDP A 501 |
| Chain | Residue |
| A | GLY31 |
| A | LYS135 |
| A | ASP137 |
| A | LEU138 |
| A | SER164 |
| A | ALA165 |
| A | ALA166 |
| A | MG502 |
| A | HOH618 |
| A | VAL32 |
| A | GLY33 |
| A | LYS34 |
| A | SER35 |
| A | ALA36 |
| A | PHE46 |
| A | GLU48 |
| A | ASN134 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 502 |
| Chain | Residue |
| A | SER35 |
| A | GDP501 |
| A | HOH618 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"40934300","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"9MEY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MF1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"40934300","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9MEY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MF1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"40934300","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9MEY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
