4KJD
RatIntestinal AP expressed in E. coli
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0002020 | molecular_function | protease binding |
| A | 0004035 | molecular_function | alkaline phosphatase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009897 | cellular_component | external side of plasma membrane |
| A | 0016311 | biological_process | dephosphorylation |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016791 | molecular_function | phosphatase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071773 | biological_process | cellular response to BMP stimulus |
| A | 0098552 | cellular_component | side of membrane |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0002020 | molecular_function | protease binding |
| B | 0004035 | molecular_function | alkaline phosphatase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0009897 | cellular_component | external side of plasma membrane |
| B | 0016311 | biological_process | dephosphorylation |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016791 | molecular_function | phosphatase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0071773 | biological_process | cellular response to BMP stimulus |
| B | 0098552 | cellular_component | side of membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 501 |
| Chain | Residue |
| A | SER155 |
| A | GLU311 |
| A | HOH734 |
| A | HOH735 |
| A | HOH736 |
| A | HOH737 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 502 |
| Chain | Residue |
| A | ASP285 |
| A | HOH634 |
| A | GLU216 |
| A | PHE269 |
| A | GLU270 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 503 |
| Chain | Residue |
| A | LYS34 |
| A | ASN35 |
| A | SER300 |
| A | THR345 |
| A | ASN346 |
| A | ASP349 |
| A | THR350 |
| A | HOH651 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 501 |
| Chain | Residue |
| B | SER155 |
| B | GLU311 |
| B | HOH704 |
| B | HOH737 |
| B | HOH738 |
| B | HOH739 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 502 |
| Chain | Residue |
| B | GLU216 |
| B | PHE269 |
| B | GLU270 |
| B | ASP285 |
| B | HOH609 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 503 |
| Chain | Residue |
| B | LYS34 |
| B | ASN35 |
| B | SER300 |
| B | ASN346 |
| B | ASP349 |
| B | THR350 |
| B | HOH631 |
Functional Information from PROSITE/UniProt
| site_id | PS00123 |
| Number of Residues | 9 |
| Details | ALKALINE_PHOSPHATASE Alkaline phosphatase active site. VpDSAGTAT |
| Chain | Residue | Details |
| A | VAL89-THR97 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphoserine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU10042","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24076154","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24076154","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P05186","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"24076154","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
