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4KFC

Crystal structure of a hyperactive mutant of response regulator KdpE complexed to its promoter DNA

Functional Information from GO Data
ChainGOidnamespacecontents
A0000156molecular_functionphosphorelay response regulator activity
A0000160biological_processphosphorelay signal transduction system
A0000976molecular_functiontranscription cis-regulatory region binding
A0000987molecular_functioncis-regulatory region sequence-specific DNA binding
A0001216molecular_functionDNA-binding transcription activator activity
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006351biological_processDNA-templated transcription
A0006355biological_processregulation of DNA-templated transcription
A0032993cellular_componentprotein-DNA complex
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0045893biological_processpositive regulation of DNA-templated transcription
B0000156molecular_functionphosphorelay response regulator activity
B0000160biological_processphosphorelay signal transduction system
B0000976molecular_functiontranscription cis-regulatory region binding
B0000987molecular_functioncis-regulatory region sequence-specific DNA binding
B0001216molecular_functionDNA-binding transcription activator activity
B0003677molecular_functionDNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006351biological_processDNA-templated transcription
B0006355biological_processregulation of DNA-templated transcription
B0032993cellular_componentprotein-DNA complex
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0045893biological_processpositive regulation of DNA-templated transcription
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues226
DetailsDomain: {"description":"Response regulatory","evidences":[{"source":"PROSITE-ProRule","id":"PRU00169","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues198
DetailsDNA binding: {"description":"OmpR/PhoB-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01091","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues2
DetailsModified residue: {"description":"4-aspartylphosphate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00169","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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