4K47

Structure of the Streptococcus pneumoniae leucyl-tRNA synthetase editing domain bound to a benzoxaborole-AMP adduct

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0002161	molecular_function	aminoacyl-tRNA deacylase activity
A	0004823	molecular_function	leucine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006429	biological_process	leucyl-tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE WMP A 501

Chain	Residue
A	PHE246
A	MET338
A	HIS343
A	ASP344
A	THR373
A	HOH607
A	HOH609
A	HOH610
A	HOH660
A	HOH685
A	HOH721
A	THR247
A	HOH724
A	THR248
A	ARG249
A	TYR327
A	VAL328
A	LEU329
A	TYR332
A	VAL337

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 502

Chain	Residue
A	SER273
A	SER274
A	HOH621

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 503

Chain	Residue
A	LYS300
A	GLU301
A	HOH680

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 504

Chain	Residue
A	PHE243
A	THR244
A	HOH679
A	HOH690

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 505

Chain	Residue
A	THR239
A	ASP240
A	LYS241

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