4K35
The structure of a glycoside hydrolase family 81 endo-[beta]-1,3-glucanase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008152 | biological_process | metabolic process |
| A | 0009986 | cellular_component | cell surface |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0042973 | molecular_function | glucan endo-1,3-beta-D-glucosidase activity |
| A | 0052861 | molecular_function | glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group |
| A | 0052862 | molecular_function | glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group |
| A | 0071555 | biological_process | cell wall organization |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0005576 | cellular_component | extracellular region |
| B | 0008152 | biological_process | metabolic process |
| B | 0009986 | cellular_component | cell surface |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0042973 | molecular_function | glucan endo-1,3-beta-D-glucosidase activity |
| B | 0052861 | molecular_function | glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group |
| B | 0052862 | molecular_function | glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group |
| B | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TRS A 801 |
| Chain | Residue |
| A | TYR386 |
| A | PHE468 |
| A | ASP475 |
| A | TYR478 |
| A | HIS479 |
| A | GLU557 |
| A | HOH1091 |
| A | HOH1454 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE TRS A 802 |
| Chain | Residue |
| A | GLU634 |
| A | THR672 |
| A | HOH1081 |
| A | HOH1094 |
| A | ASP98 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TRS B 801 |
| Chain | Residue |
| B | TYR386 |
| B | PHE468 |
| B | ASP475 |
| B | TYR478 |
| B | HIS479 |
| B | GLU557 |
| B | TYR628 |
| B | HOH954 |
| B | HOH1398 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE TRS B 802 |
| Chain | Residue |
| B | GLU634 |
| B | THR672 |
| B | HOH1119 |
| B | HOH1180 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 803 |
| Chain | Residue |
| A | ILE687 |
| A | PRO719 |
| B | PRO655 |
| B | ILE687 |
| B | HIS720 |
| B | HOH1524 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01352, ECO:0000305|PubMed:34801773, ECO:0007744|PDB:5XBZ, ECO:0007744|PDB:5XC2 |
| Chain | Residue | Details |
| A | ASP475 | |
| B | ASP475 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01352 |
| Chain | Residue | Details |
| A | GLU553 | |
| B | GLU553 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01352, ECO:0000305|PubMed:24100321, ECO:0000305|PubMed:34801773, ECO:0007744|PDB:4K35, ECO:0007744|PDB:4K3A, ECO:0007744|PDB:5XBZ, ECO:0007744|PDB:5XC2 |
| Chain | Residue | Details |
| A | GLU557 | |
| B | GLU557 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:34801773, ECO:0007744|PDB:5XC2 |
| Chain | Residue | Details |
| A | HIS479 | |
| B | TYR635 | |
| A | ASP551 | |
| A | GLU553 | |
| A | GLU557 | |
| A | TYR635 | |
| B | HIS479 | |
| B | ASP551 | |
| B | GLU553 | |
| B | GLU557 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 |
| Chain | Residue | Details |
| A | ASN194 | |
| A | ASN375 | |
| A | ASN403 | |
| B | ASN194 | |
| B | ASN375 | |
| B | ASN403 |
