4K22
Structure of the C-terminal truncated form of E.Coli C5-hydroxylase UBII involved in ubiquinone (Q8) biosynthesis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006744 | biological_process | ubiquinone biosynthetic process |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0019168 | molecular_function | 2-octaprenylphenol hydroxylase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0071949 | molecular_function | FAD binding |
| A | 0110142 | cellular_component | ubiquinone biosynthesis complex |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006744 | biological_process | ubiquinone biosynthetic process |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0019168 | molecular_function | 2-octaprenylphenol hydroxylase activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0071949 | molecular_function | FAD binding |
| B | 0110142 | cellular_component | ubiquinone biosynthesis complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 501 |
| Chain | Residue |
| A | ARG49 |
| A | VAL226 |
| A | PHE269 |
| A | GLN300 |
| A | GOL507 |
| A | HOH632 |
| A | HOH706 |
| A | HOH707 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 502 |
| Chain | Residue |
| A | ARG333 |
| B | TRP140 |
| B | ALA174 |
| B | SER281 |
| B | HIS282 |
| A | TYR329 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 503 |
| Chain | Residue |
| A | GLY65 |
| A | TRP67 |
| A | GLN68 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 504 |
| Chain | Residue |
| A | TRP84 |
| A | ASP254 |
| A | ARG256 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 505 |
| Chain | Residue |
| A | GLN204 |
| A | HIS295 |
| A | PRO296 |
| A | LEU297 |
| A | ALA298 |
| A | HOH677 |
| A | HOH845 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 506 |
| Chain | Residue |
| A | ASP175 |
| A | TRP181 |
| A | ASP182 |
| A | HOH601 |
| A | HOH702 |
| B | ARG277 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 507 |
| Chain | Residue |
| A | PRO270 |
| A | THR272 |
| A | GOL501 |
| A | HOH612 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 501 |
| Chain | Residue |
| B | GLN204 |
| B | HIS295 |
| B | PRO296 |
| B | LEU297 |
| B | ALA298 |
| B | HOH755 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 502 |
| Chain | Residue |
| A | GLN328 |
| A | ILE330 |
| B | TYR329 |
| B | ILE330 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 503 |
| Chain | Residue |
| B | GLY65 |
| B | TRP67 |
| B | GLN68 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 504 |
| Chain | Residue |
| B | ARG49 |
| B | VAL226 |
| B | PHE269 |
| B | ILE294 |
| B | GLN300 |
| B | GOL505 |
| B | HOH637 |
| B | HOH662 |
| B | HOH710 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 505 |
| Chain | Residue |
| B | PRO270 |
| B | LEU271 |
| B | THR272 |
| B | GOL504 |
| B | HOH628 |
Functional Information from PROSITE/UniProt
| site_id | PS01304 |
| Number of Residues | 14 |
| Details | UBIH ubiH/COQ6 monooxygenase family signature. HPLAGQGvNlGfmD |
| Chain | Residue | Details |
| A | HIS295-ASP308 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | ARG49 | |
| A | LEU297 | |
| B | ARG49 | |
| B | LEU297 |
