4K17
Crystal Structure of mouse CARMIL residues 1-668
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0030027 | cellular_component | lamellipodium |
| A | 0030335 | biological_process | positive regulation of cell migration |
| A | 0051638 | biological_process | barbed-end actin filament uncapping |
| A | 1902745 | biological_process | positive regulation of lamellipodium organization |
| A | 2000813 | biological_process | negative regulation of barbed-end actin filament capping |
| B | 0030027 | cellular_component | lamellipodium |
| B | 0030335 | biological_process | positive regulation of cell migration |
| B | 0051638 | biological_process | barbed-end actin filament uncapping |
| B | 1902745 | biological_process | positive regulation of lamellipodium organization |
| B | 2000813 | biological_process | negative regulation of barbed-end actin filament capping |
| C | 0030027 | cellular_component | lamellipodium |
| C | 0030335 | biological_process | positive regulation of cell migration |
| C | 0051638 | biological_process | barbed-end actin filament uncapping |
| C | 1902745 | biological_process | positive regulation of lamellipodium organization |
| C | 2000813 | biological_process | negative regulation of barbed-end actin filament capping |
| D | 0030027 | cellular_component | lamellipodium |
| D | 0030335 | biological_process | positive regulation of cell migration |
| D | 0051638 | biological_process | barbed-end actin filament uncapping |
| D | 1902745 | biological_process | positive regulation of lamellipodium organization |
| D | 2000813 | biological_process | negative regulation of barbed-end actin filament capping |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE OHB B 701 |
| Chain | Residue |
| A | GLU380 |
| A | SER384 |
| A | SER415 |
| B | GLU380 |
| B | MSE381 |
| B | SER384 |
| B | PRO413 |
| B | SER415 |
| B | CL702 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 702 |
| Chain | Residue |
| A | ARG388 |
| A | SER415 |
| B | ARG388 |
| B | SER415 |
| B | OHB701 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ABU C 701 |
| Chain | Residue |
| C | ASN282 |
| C | HIS309 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 96 |
| Details | Repeat: {"description":"LRR 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 92 |
| Details | Repeat: {"description":"LRR 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 92 |
| Details | Repeat: {"description":"LRR 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 108 |
| Details | Repeat: {"description":"LRR 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | Repeat: {"description":"LRR 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 100 |
| Details | Repeat: {"description":"LRR 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 92 |
| Details | Repeat: {"description":"LRR 8"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q5VZK9","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
