4JZJ

Crystal Structure of Receptor-Fab Complex

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Functional Information from GO Data

ChainGOidnamespacecontents
C0009897cellular_componentexternal side of plasma membrane
C0016021cellular_componentintegral component of membrane
C0005886cellular_componentplasma membrane
C0043235cellular_componentreceptor complex
C0019955molecular_functioncytokine binding
C0004896molecular_functioncytokine receptor activity
C0004912molecular_functioninterleukin-3 receptor activity
C0019221biological_processcytokine-mediated signaling pathway
C0000165biological_processMAPK cascade
D0009897cellular_componentexternal side of plasma membrane
D0016021cellular_componentintegral component of membrane
D0005886cellular_componentplasma membrane
D0043235cellular_componentreceptor complex
D0019955molecular_functioncytokine binding
D0004896molecular_functioncytokine receptor activity
D0004912molecular_functioninterleukin-3 receptor activity
D0019221biological_processcytokine-mediated signaling pathway
D0000165biological_processMAPK cascade
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC12BINDING SITE FOR RESIDUE NAG D 409
ChainResidue
DFUL406
DNAG407

AC21BINDING SITE FOR RESIDUE GOL D 410
ChainResidue
DARG184

AC39BINDING SITE FOR RESIDUE GOL H 301
ChainResidue
HPRO174
HVAL176
HSER184
HLEU185
HSER186
HHOH409
LSER168
LSER182
LTHR184

AC42BINDING SITE FOR MONO-SACCHARIDE NAG C 408 BOUND TO ASN C 46
ChainResidue
CASN46
CTHR48

AC514BINDING SITE FOR CHAIN C OF SUGAR BOUND TO ASN C 80 RESIDUES 401 TO 407
ChainResidue
CALA56
CASN80
CTHR82
CSER91
CTRP93
CLEU95
CHOH501
HASN55
HALA57
HTHR58
HPHE59
HTYR60
HGLN62
HLYS65

AC66BINDING SITE FOR CHAIN D OF SUGAR BOUND TO ASN D 80 RESIDUES 401 TO 405
ChainResidue
AALA57
ATHR58
APHE59
DASN80
DTHR82
DTRP93

AC77BINDING SITE FOR CHAIN D OF SUGAR BOUND TO ASN D 109 RESIDUES 406 TO 408
ChainResidue
CASP118
CARG171
CARG228
DGLU108
DASN109
DALA125
DNAG409

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
NAG_4jzj_C_4083N-ACETYL-D-GLUCOSAMINE binding site
ChainResidueligand
CASN46-THR48NAG: N-ACETYL-D-GLUCOSAMINE

FUL_4jzj_C_4029BETA-L-FUCOSE binding site
ChainResidueligand
CVAL53FUL: BETA-L-FUCOSE
CALA56FUL: BETA-L-FUCOSE
CTHR82FUL: BETA-L-FUCOSE
HTHR58-TYR60FUL: BETA-L-FUCOSE
HGLN62FUL: BETA-L-FUCOSE
HLYS65FUL: BETA-L-FUCOSE
LTYR100FUL: BETA-L-FUCOSE

NAG_4jzj_C_4015N-ACETYL-D-GLUCOSAMINE binding site
ChainResidueligand
CASN80NAG: N-ACETYL-D-GLUCOSAMINE
CTHR82NAG: N-ACETYL-D-GLUCOSAMINE
CTRP93NAG: N-ACETYL-D-GLUCOSAMINE
CLEU95NAG: N-ACETYL-D-GLUCOSAMINE
HTHR58NAG: N-ACETYL-D-GLUCOSAMINE

NAG_4jzj_C_4037N-ACETYL-D-GLUCOSAMINE binding site
ChainResidueligand
CTHR82NAG: N-ACETYL-D-GLUCOSAMINE
CSER91NAG: N-ACETYL-D-GLUCOSAMINE
CTRP93NAG: N-ACETYL-D-GLUCOSAMINE
HGLY56-PHE59NAG: N-ACETYL-D-GLUCOSAMINE

FUL_4jzj_C_4071BETA-L-FUCOSE binding site
ChainResidueligand
CTRP93FUL: BETA-L-FUCOSE

FUL_4jzj_D_4047BETA-L-FUCOSE binding site
ChainResidueligand
DVAL53FUL: BETA-L-FUCOSE
DALA56FUL: BETA-L-FUCOSE
DTHR82FUL: BETA-L-FUCOSE
ATHR58-TYR60FUL: BETA-L-FUCOSE
ALYS65FUL: BETA-L-FUCOSE

GOL_4jzj_D_4105GLYCEROL binding site
ChainResidueligand
DLEU75GOL: GLYCEROL
DPHE96GOL: GLYCEROL
DLEU182GOL: GLYCEROL
DARG184GOL: GLYCEROL
DCYS194GOL: GLYCEROL

NAG_4jzj_D_4014N-ACETYL-D-GLUCOSAMINE binding site
ChainResidueligand
DASN80NAG: N-ACETYL-D-GLUCOSAMINE
DTHR82NAG: N-ACETYL-D-GLUCOSAMINE
DTRP93NAG: N-ACETYL-D-GLUCOSAMINE
DLEU95NAG: N-ACETYL-D-GLUCOSAMINE

NAG_4jzj_D_4027N-ACETYL-D-GLUCOSAMINE binding site
ChainResidueligand
DTHR82NAG: N-ACETYL-D-GLUCOSAMINE
DSER91NAG: N-ACETYL-D-GLUCOSAMINE
DTRP93NAG: N-ACETYL-D-GLUCOSAMINE
AGLY56-PHE59NAG: N-ACETYL-D-GLUCOSAMINE

FUL_4jzj_D_4051BETA-L-FUCOSE binding site
ChainResidueligand
DTRP93FUL: BETA-L-FUCOSE

NAG_4jzj_D_4074N-ACETYL-D-GLUCOSAMINE binding site
ChainResidueligand
DGLU108-ASN109NAG: N-ACETYL-D-GLUCOSAMINE
DALA125-VAL126NAG: N-ACETYL-D-GLUCOSAMINE

FUC_4jzj_D_4082ALPHA-L-FUCOSE binding site
ChainResidueligand
DGLU108FUC: ALPHA-L-FUCOSE
DPRO128FUC: ALPHA-L-FUCOSE

FUL_4jzj_D_4061BETA-L-FUCOSE binding site
ChainResidueligand
DASN109FUL: BETA-L-FUCOSE

BMA_4jzj_D_4033BETA-D-MANNOSE binding site
ChainResidueligand
AGLY56-THR58BMA: BETA-D-MANNOSE

MAN_4jzj_C_4053ALPHA-D-MANNOSE binding site
ChainResidueligand
HASN55-ALA57MAN: ALPHA-D-MANNOSE

BMA_4jzj_C_4045BETA-D-MANNOSE binding site
ChainResidueligand
HASN55-THR58BMA: BETA-D-MANNOSE
HTYR60BMA: BETA-D-MANNOSE

GOL_4jzj_H_30113GLYCEROL binding site
ChainResidueligand
HLEU148GOL: GLYCEROL
HPHE173-VAL176GOL: GLYCEROL
HSER184-SER186GOL: GLYCEROL
LVAL139GOL: GLYCEROL
LGLN166GOL: GLYCEROL
LSER168GOL: GLYCEROL
LSER182GOL: GLYCEROL
LTHR184GOL: GLYCEROL

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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI120Helical. {ECO:0000255}.
ChainResidueDetails
CNA*

SWS_FT_FI220Helical. {ECO:0000255}.
ChainResidueDetails
DNA*

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Catalytic Information from CSA

site_idNumber of ResiduesDetails