4JXT

CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0099122	molecular_function	RNA polymerase II C-terminal domain binding
B	0003677	molecular_function	DNA binding
B	0006366	biological_process	transcription by RNA polymerase II

Functional Information from PDB Data

site_id	AC1
Number of Residues	28
Details	BINDING SITE FOR CHAIN B OF DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1

Chain	Residue
A	ASN18
A	GLN68
A	LYS71
A	ARG72
A	LYS73
A	GLU76
A	ARG106
A	ILE110
A	ARG114
A	SER115
A	VAL116
A	SER19
B	HOH1701
B	HOH1702
B	HOH1703
B	HOH1704
B	HOH1705
B	HOH1706
B	HOH1707
B	HOH1708
B	HOH1709
A	GLN20
A	VAL23
A	ARG34
A	LYS35
A	TYR61
A	ASN64
A	ASP65

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Functional Information from PROSITE/UniProt

site_id	PS00115
Number of Residues	7
Details	RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPS

Chain	Residue	Details
B	TYR1622-SEP1628
B	TYR1629-SEP1635

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JAN-2010","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Bilsland A.E.","Keith W.N."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6,N6-dimethyllysine","evidences":[{"source":"UniProtKB","id":"P08775","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"26566685","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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