4JWX
GluN2A ligand-binding core in complex with propyl-NHP5G
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1N4 A 301 |
| Chain | Residue |
| A | HIS88 |
| A | HOH430 |
| A | HOH468 |
| A | SER114 |
| A | THR116 |
| A | ARG121 |
| A | VAL169 |
| A | GLY172 |
| A | SER173 |
| A | THR174 |
| A | TYR214 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 39 |
| Details | TRANSMEM: Helical => ECO:0000250|UniProtKB:B7ZSK1 |
| Chain | Residue | Details |
| A | ASP159-ARG179 | |
| A | CYS229-ALA248 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 27 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | ASN180-SER203 | |
| A | GLY224-GLY228 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 19 |
| Details | INTRAMEM: Discontinuously helical => ECO:0000250|UniProtKB:B7ZSK1 |
| Chain | Residue | Details |
| A | LEU204-ALA223 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16281028, ECO:0007744|PDB:2A5S, ECO:0007744|PDB:2A5T, ECO:0007744|PDB:4NF4, ECO:0007744|PDB:4NF8, ECO:0007744|PDB:5I56, ECO:0007744|PDB:5I57, ECO:0007744|PDB:5I58, ECO:0007744|PDB:5I59, ECO:0007744|PDB:5JTY |
| Chain | Residue | Details |
| A | SER114 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16281028, ECO:0000269|PubMed:24462099, ECO:0000269|PubMed:27618671, ECO:0007744|PDB:2A5S, ECO:0007744|PDB:2A5T, ECO:0007744|PDB:4NF4, ECO:0007744|PDB:4NF8, ECO:0007744|PDB:5I56, ECO:0007744|PDB:5I57, ECO:0007744|PDB:5I58, ECO:0007744|PDB:5I59, ECO:0007744|PDB:5JTY |
| Chain | Residue | Details |
| A | ARG121 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16281028, ECO:0000269|PubMed:24462099, ECO:0007744|PDB:2A5S, ECO:0007744|PDB:2A5T, ECO:0007744|PDB:4NF4, ECO:0007744|PDB:4NF8 |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | SITE: Functional determinant of NMDA receptors => ECO:0000250 |
| Chain | Residue | Details |
| A | ALA217 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN46 | |
| A | ASN47 | |
| A | THR144 |
