4JWR
Co-crystal structure of MDM2 with inhibitor {(2S,5R,6S)-6-(3-chlorophenyl)-5-(4-chlorophenyl)-4-[(2S)-1-hydroxybutan-2-yl]-3-oxomorpholin-2-yl}acetic acid
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005634 | cellular_component | nucleus |
A | 0043066 | biological_process | negative regulation of apoptotic process |
A | 0051726 | biological_process | regulation of cell cycle |
B | 0005634 | cellular_component | nucleus |
B | 0043066 | biological_process | negative regulation of apoptotic process |
B | 0051726 | biological_process | regulation of cell cycle |
C | 0005634 | cellular_component | nucleus |
C | 0043066 | biological_process | negative regulation of apoptotic process |
C | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE 1MY A 201 |
Chain | Residue |
A | LEU54 |
A | VAL93 |
A | HIS96 |
A | ILE99 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE 1MY B 201 |
Chain | Residue |
B | LEU54 |
B | VAL93 |
B | HIS96 |
B | ILE99 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE 1MY C 201 |
Chain | Residue |
C | VAL93 |
C | HIS96 |
C | ILE99 |
C | LEU54 |