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4JWR

Co-crystal structure of MDM2 with inhibitor {(2S,5R,6S)-6-(3-chlorophenyl)-5-(4-chlorophenyl)-4-[(2S)-1-hydroxybutan-2-yl]-3-oxomorpholin-2-yl}acetic acid

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0043066biological_processnegative regulation of apoptotic process
A0051726biological_processregulation of cell cycle
B0005634cellular_componentnucleus
B0043066biological_processnegative regulation of apoptotic process
B0051726biological_processregulation of cell cycle
C0005634cellular_componentnucleus
C0043066biological_processnegative regulation of apoptotic process
C0051726biological_processregulation of cell cycle
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE 1MY A 201
ChainResidue
ALEU54
AVAL93
AHIS96
AILE99

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE 1MY B 201
ChainResidue
BLEU54
BVAL93
BHIS96
BILE99

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE 1MY C 201
ChainResidue
CVAL93
CHIS96
CILE99
CLEU54

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PDB entries from 2024-07-17

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