4JUQ
Pseudomonas aeruginosa MetAP T2N mutant, in Mn form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0004239 | molecular_function | initiator methionyl aminopeptidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008235 | molecular_function | metalloexopeptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070006 | molecular_function | metalloaminopeptidase activity |
| B | 0004177 | molecular_function | aminopeptidase activity |
| B | 0004239 | molecular_function | initiator methionyl aminopeptidase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006508 | biological_process | proteolysis |
| B | 0008235 | molecular_function | metalloexopeptidase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070006 | molecular_function | metalloaminopeptidase activity |
| C | 0004177 | molecular_function | aminopeptidase activity |
| C | 0004239 | molecular_function | initiator methionyl aminopeptidase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006508 | biological_process | proteolysis |
| C | 0008235 | molecular_function | metalloexopeptidase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0070006 | molecular_function | metalloaminopeptidase activity |
| D | 0004177 | molecular_function | aminopeptidase activity |
| D | 0004239 | molecular_function | initiator methionyl aminopeptidase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006508 | biological_process | proteolysis |
| D | 0008235 | molecular_function | metalloexopeptidase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0070006 | molecular_function | metalloaminopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 301 |
| Chain | Residue |
| A | ASP107 |
| A | HIS170 |
| A | GLU203 |
| A | GLU234 |
| A | MN302 |
| A | HOH431 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 302 |
| Chain | Residue |
| A | MN301 |
| A | HOH431 |
| A | HOH432 |
| A | ASP96 |
| A | ASP107 |
| A | GLU234 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 303 |
| Chain | Residue |
| A | HIS144 |
| A | HOH428 |
| B | HIS144 |
| B | GLU193 |
| B | HOH433 |
| B | HOH434 |
| B | HOH435 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 304 |
| Chain | Residue |
| A | ASN74 |
| A | VAL76 |
| A | SER230 |
| A | HOH429 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B 301 |
| Chain | Residue |
| B | ASP107 |
| B | HIS170 |
| B | THR201 |
| B | GLU203 |
| B | GLU234 |
| B | MN302 |
| B | HOH439 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 302 |
| Chain | Residue |
| B | ASP96 |
| B | ASP107 |
| B | GLU234 |
| B | MN301 |
| B | HOH439 |
| B | HOH440 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 303 |
| Chain | Residue |
| B | ASN74 |
| B | VAL76 |
| B | SER230 |
| B | HOH436 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN C 301 |
| Chain | Residue |
| C | ASP107 |
| C | HIS170 |
| C | GLU203 |
| C | GLU234 |
| C | MN302 |
| C | HOH427 |
| C | HOH438 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN C 302 |
| Chain | Residue |
| C | ASP96 |
| C | ASP107 |
| C | GLU234 |
| C | MN301 |
| C | HOH427 |
| C | HOH428 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN C 303 |
| Chain | Residue |
| C | ASN74 |
| C | VAL76 |
| C | SER230 |
| C | HOH419 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN D 301 |
| Chain | Residue |
| D | ASP107 |
| D | HIS170 |
| D | THR201 |
| D | GLU203 |
| D | GLU234 |
| D | MN302 |
| D | HOH430 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN D 302 |
| Chain | Residue |
| D | ASP96 |
| D | ASP107 |
| D | GLU234 |
| D | MN301 |
| D | HOH428 |
| D | HOH430 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MN D 303 |
| Chain | Residue |
| D | HIS144 |
| D | GLU193 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN D 304 |
| Chain | Residue |
| D | ASN74 |
| D | VAL76 |
| D | SER230 |
| D | HOH402 |
Functional Information from PROSITE/UniProt
| site_id | PS00680 |
| Number of Residues | 19 |
| Details | MAP_1 Methionine aminopeptidase subfamily 1 signature. YcGHGIGkvfHeepqVl.HY |
| Chain | Residue | Details |
| A | TYR167-TYR185 |
