4JQU
Crystal structure of Ubc7p in complex with the U7BR of Cue1p
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000209 | biological_process | protein polyubiquitination |
| A | 0000837 | cellular_component | Doa10p ubiquitin ligase complex |
| A | 0000839 | cellular_component | Hrd1p ubiquitin ligase ERAD-L complex |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0006325 | biological_process | chromatin organization |
| A | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0016740 | molecular_function | transferase activity |
| A | 0031505 | biological_process | fungal-type cell wall organization |
| A | 0036503 | biological_process | ERAD pathway |
| A | 0046686 | biological_process | response to cadmium ion |
| A | 0061631 | molecular_function | ubiquitin conjugating enzyme activity |
| A | 1990389 | cellular_component | CUE1-UBC7 ubiquitin-conjugating enzyme complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BTB A 301 |
| Chain | Residue |
| A | LYS29 |
| A | ASP38 |
| A | HOH481 |
| A | HOH497 |
| B | LYS154 |
| B | PHE155 |
| B | HIS156 |
| B | GLU174 |
| B | LYS177 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 302 |
| Chain | Residue |
| A | GLY23 |
| A | ILE24 |
| A | HOH492 |
| A | HOH493 |
| B | LEU180 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 303 |
| Chain | Residue |
| A | SER76 |
| A | ILE77 |
| A | LEU78 |
| A | ASN137 |
| A | HOH476 |
Functional Information from PROSITE/UniProt
| site_id | PS00183 |
| Number of Residues | 16 |
| Details | UBC_1 Ubiquitin-conjugating (UBC) active site signature. LHPNIypn.GeVCIsiL |
| Chain | Residue | Details |
| A | LEU78-LEU93 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388 |
| Chain | Residue | Details |
| A | CYS89 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl cysteine thioester (Cys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:17310239 |
| Chain | Residue | Details |
| A | CYS89 |
