4JN1

An Antidote for Dabigatran

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL H 301

Chain	Residue
H	ILE34
H	ASP36
H	VAL51
H	TRP53
H	GLY109
H	PHE110
H	GOL302
L	HIS102
L	HOH595

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL H 302

Chain	Residue
H	TYR107
H	CYS226
H	GOL301
H	HOH441
H	HOH453
L	TYR32
L	TYR38
L	SER97
L	HOH461

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL H 303

Chain	Residue
H	GLY9
H	PRO10
H	GLY11
H	VAL13
H	LEU19
H	SER20
H	HOH421
H	HOH504

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL H 304

Chain	Residue
H	SER32
H	TYR33
H	ALA54
H	LYS72
H	PHE79

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL H 305

Chain	Residue
H	TYR102
H	ASN106
H	GOL306
L	VAL64
L	PRO65
L	ASP66
L	HOH529

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site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL H 306

Chain	Residue
H	ASN106
H	TYR107
H	GOL305
L	LYS36
L	TYR38
L	TYR55
L	GOL302

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site_id	AC7
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GOL L 301

Chain	Residue
H	PHE176
H	PRO177
H	VAL179
H	SER187
H	LEU188
H	SER189
L	GLN166
L	SER168
L	SER182
L	SER183
L	THR184
L	HOH439

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site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL L 302

Chain	Residue
H	TYR102
H	ASP108
H	GOL306
L	ARG52
L	TYR55
L	ASP61
L	SER62
L	GLY63
L	HOH584

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR204-HIS210
L	TYR198-HIS204

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