4JMX
Structure of LD transpeptidase LdtMt1 in complex with imipenem
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008360 | biological_process | regulation of cell shape |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0018104 | biological_process | peptidoglycan-protein cross-linking |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0071555 | biological_process | cell wall organization |
| A | 0071972 | molecular_function | peptidoglycan L,D-transpeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE IM2 A 301 |
| Chain | Residue |
| A | MET175 |
| A | ASN228 |
| A | HOH474 |
| A | TYR190 |
| A | GLY204 |
| A | HIS208 |
| A | TRP212 |
| A | SER223 |
| A | HIS224 |
| A | GLY225 |
| A | CYS226 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 125 |
| Details | Domain: {"description":"L,D-TPase catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23999293","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23999293","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"NOV-2013","submissionDatabase":"EMBL/GenBank/DDBJ databases","title":"The genome sequence of Mycobacterium tuberculosis H37Rv.","authoringGroup":["The Broad Institute Genome Sequencing Platform"],"authors":["Galagan J.","Kreiswirth B.","Dobos K.","Fortune S.","Fitzgerald M.","Young S.K.","Zeng Q.","Gargeya S.","Abouelleil A.","Alvarado L.","Berlin A.M.","Chapman S.B.","Gainer-Dewar J.","Goldberg J.","Gnerre S.","Griggs A.","Gujja S.","Hansen M.","Howarth C.","Imamovic A.","Larimer J.","McCowan C.","Murphy C.","Pearson M.","Poon T.","Priest M.","Roberts A.","Saif S.","Shea T.","Sykes S.","Wortman J.","Nusbaum C.","Birren B."]}},{"source":"PDB","id":"4JMX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"covalent","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"NOV-2013","submissionDatabase":"EMBL/GenBank/DDBJ databases","title":"The genome sequence of Mycobacterium tuberculosis H37Rv.","authoringGroup":["The Broad Institute Genome Sequencing Platform"],"authors":["Galagan J.","Kreiswirth B.","Dobos K.","Fortune S.","Fitzgerald M.","Young S.K.","Zeng Q.","Gargeya S.","Abouelleil A.","Alvarado L.","Berlin A.M.","Chapman S.B.","Gainer-Dewar J.","Goldberg J.","Gnerre S.","Griggs A.","Gujja S.","Hansen M.","Howarth C.","Imamovic A.","Larimer J.","McCowan C.","Murphy C.","Pearson M.","Poon T.","Priest M.","Roberts A.","Saif S.","Shea T.","Sykes S.","Wortman J.","Nusbaum C.","Birren B."]}},{"source":"PDB","id":"4JMX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
