4JAV
Structural basis of a rationally rewired protein-protein interface (HK853wt and RR468mutant V13P, L14I, I17M and N21V)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| C | 0000156 | molecular_function | phosphorelay response regulator activity |
| C | 0000160 | biological_process | phosphorelay signal transduction system |
| C | 0003677 | molecular_function | DNA binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000156 | molecular_function | phosphorelay response regulator activity |
| D | 0000160 | biological_process | phosphorelay signal transduction system |
| D | 0003677 | molecular_function | DNA binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | LYS239 |
| A | ARG243 |
| A | ARG246 |
| A | ARG423 |
| A | TYR429 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | HOH608 |
| A | ASN379 |
| A | LYS383 |
| A | MG503 |
| A | ADP504 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 503 |
| Chain | Residue |
| A | ASN379 |
| A | ASN380 |
| A | LYS383 |
| A | SO4502 |
| A | ADP504 |
| A | HOH608 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP A 504 |
| Chain | Residue |
| A | ASN380 |
| A | LYS383 |
| A | TYR384 |
| A | ASP411 |
| A | ILE416 |
| A | ILE424 |
| A | TYR429 |
| A | ARG430 |
| A | VAL431 |
| A | GLY441 |
| A | THR442 |
| A | GLY443 |
| A | GLY445 |
| A | LEU446 |
| A | SER470 |
| A | PHE472 |
| A | SO4502 |
| A | MG503 |
| A | HOH608 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 501 |
| Chain | Residue |
| A | HIS260 |
| B | ARG314 |
| B | ARG317 |
| B | SER319 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 502 |
| Chain | Residue |
| A | ARG314 |
| A | ARG317 |
| B | HIS260 |
| B | LYS386 |
| B | LYS387 |
| B | ASP388 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 503 |
| Chain | Residue |
| B | ASN379 |
| B | LYS383 |
| B | PRO440 |
| B | GLY441 |
| B | THR442 |
| B | ADP505 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 504 |
| Chain | Residue |
| B | ASN380 |
| B | LYS383 |
| B | ADP505 |
| site_id | AC9 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ADP B 505 |
| Chain | Residue |
| B | ASN380 |
| B | LYS383 |
| B | TYR384 |
| B | ASP411 |
| B | ILE414 |
| B | ILE416 |
| B | ILE424 |
| B | TYR429 |
| B | ARG430 |
| B | VAL431 |
| B | GLY441 |
| B | GLY443 |
| B | GLY445 |
| B | LEU446 |
| B | SER470 |
| B | PHE472 |
| B | SO4503 |
| B | MG504 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 506 |
| Chain | Residue |
| B | ARG314 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 201 |
| Chain | Residue |
| C | ASP10 |
| C | BFD53 |
| C | MET55 |
| C | HOH304 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG D 201 |
| Chain | Residue |
| D | ASP10 |
| D | BFD53 |
| D | MET55 |
