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4JAR

Crystal structure of mycobacterium tuberculosis pks11 in complex with polyketide intermediates and evidence that it synthesize ALKYLPYRONES

Functional Information from GO Data
ChainGOidnamespacecontents
A0006629biological_processlipid metabolic process
A0006631biological_processfatty acid metabolic process
A0006633biological_processfatty acid biosynthetic process
A0008610biological_processlipid biosynthetic process
A0009058biological_processbiosynthetic process
A0009715biological_processchalcone biosynthetic process
A0016740molecular_functiontransferase activity
A0016746molecular_functionacyltransferase activity
A0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
A0030639biological_processpolyketide biosynthetic process
A0034081cellular_componentpolyketide synthase complex
A0071770biological_processDIM/DIP cell wall layer assembly
B0006629biological_processlipid metabolic process
B0006631biological_processfatty acid metabolic process
B0006633biological_processfatty acid biosynthetic process
B0008610biological_processlipid biosynthetic process
B0009058biological_processbiosynthetic process
B0009715biological_processchalcone biosynthetic process
B0016740molecular_functiontransferase activity
B0016746molecular_functionacyltransferase activity
B0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
B0030639biological_processpolyketide biosynthetic process
B0034081cellular_componentpolyketide synthase complex
B0071770biological_processDIM/DIP cell wall layer assembly
C0006629biological_processlipid metabolic process
C0006631biological_processfatty acid metabolic process
C0006633biological_processfatty acid biosynthetic process
C0008610biological_processlipid biosynthetic process
C0009058biological_processbiosynthetic process
C0009715biological_processchalcone biosynthetic process
C0016740molecular_functiontransferase activity
C0016746molecular_functionacyltransferase activity
C0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
C0030639biological_processpolyketide biosynthetic process
C0034081cellular_componentpolyketide synthase complex
C0071770biological_processDIM/DIP cell wall layer assembly
D0006629biological_processlipid metabolic process
D0006631biological_processfatty acid metabolic process
D0006633biological_processfatty acid biosynthetic process
D0008610biological_processlipid biosynthetic process
D0009058biological_processbiosynthetic process
D0009715biological_processchalcone biosynthetic process
D0016740molecular_functiontransferase activity
D0016746molecular_functionacyltransferase activity
D0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
D0030639biological_processpolyketide biosynthetic process
D0034081cellular_componentpolyketide synthase complex
D0071770biological_processDIM/DIP cell wall layer assembly
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsActive site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"23615910","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues32
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"23615910","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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