4J9L

Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after a C at the primer 3' end (CA/G)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 501

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG502
A	XG4503

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A 502

Chain	Residue
A	XG4503
A	HOH605
A	HOH607
A	ASP13
A	ASP115
A	GLU116
A	MG501

---

site_id	AC3
Number of Residues	26
Details	BINDING SITE FOR RESIDUE XG4 A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	GLN38
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	MG501
A	MG502
A	HOH605
A	HOH607
A	HOH613
A	HOH637
A	HOH644
A	HOH753
A	HOH779
P	DC9
T	DT4
T	DG5

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	SER257
A	LYS293
A	ASN294
A	TRP297
A	HOH793

---

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 505

Chain	Residue
A	ARG24
A	PRO244
A	PHE247
A	SER248
A	GLY276
A	GLU277
A	HOH610
A	HOH662
A	HOH673
A	HOH674

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 506

Chain	Residue
A	ASN26
A	PRO27
A	HIS28
A	GLY271
A	GLU273
A	TYR274
A	GLU277
A	HOH788
A	HOH901

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 507

Chain	Residue
A	GLU94
A	ALA95
A	GLU98
A	HOH642
A	HOH667
A	HOH799
A	HOH891

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO

Chain	Residue	Details
A	ASP13
A	MET14
A	ASP115
A	GLU116

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197

Chain	Residue	Details
A	ARG61

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