4ISY
Crystal structure of IscS from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0016226 | biological_process | iron-sulfur cluster assembly |
| A | 0016740 | molecular_function | transferase activity |
| A | 0031071 | molecular_function | cysteine desulfurase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0016226 | biological_process | iron-sulfur cluster assembly |
| B | 0016740 | molecular_function | transferase activity |
| B | 0031071 | molecular_function | cysteine desulfurase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0016226 | biological_process | iron-sulfur cluster assembly |
| C | 0016740 | molecular_function | transferase activity |
| C | 0031071 | molecular_function | cysteine desulfurase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0008483 | molecular_function | transaminase activity |
| D | 0016226 | biological_process | iron-sulfur cluster assembly |
| D | 0016740 | molecular_function | transferase activity |
| D | 0031071 | molecular_function | cysteine desulfurase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051536 | molecular_function | iron-sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 401 |
| Chain | Residue |
| A | ARG92 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | GLY230 |
| C | HIS101 |
| C | ASP105 |
| C | ALA328 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| C | ALA7 |
| C | ALA8 |
| C | GLY326 |
| C | ARG355 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 401 |
| Chain | Residue |
| B | ARG58 |
| B | PRO59 |
| B | SER60 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 402 |
| Chain | Residue |
| B | GLU45 |
| B | GLN232 |
| B | GLU233 |
| B | ARG234 |
| B | HOH557 |
| B | HOH558 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 401 |
| Chain | Residue |
| C | ARG92 |
| C | HIS117 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 402 |
| Chain | Residue |
| A | ARG380 |
| C | HIS89 |
| D | ARG58 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 403 |
| Chain | Residue |
| C | ARG83 |
| C | THR222 |
| C | HOH540 |
| C | HOH541 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P0A6B9","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O29689","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"UniProtKB","id":"P0A6B9","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"24548275","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
