4IRK

structure of Polymerase-DNA complex, dna

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0000731	biological_process	DNA synthesis involved in DNA repair
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006259	biological_process	DNA metabolic process
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0008296	molecular_function	3'-5'-DNA exonuclease activity
A	0009432	biological_process	SOS response
A	0034061	molecular_function	DNA polymerase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
A	0070987	biological_process	error-free translesion synthesis
B	0000287	molecular_function	magnesium ion binding
B	0000731	biological_process	DNA synthesis involved in DNA repair
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006259	biological_process	DNA metabolic process
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0008296	molecular_function	3'-5'-DNA exonuclease activity
B	0009432	biological_process	SOS response
B	0034061	molecular_function	DNA polymerase activity
B	0042276	biological_process	error-prone translesion synthesis
B	0046872	molecular_function	metal ion binding
B	0070987	biological_process	error-free translesion synthesis

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE DCP B 401

Chain	Residue
B	ASP8
B	ASP103
B	GLU104
B	LYS157
B	MG402
B	HOH530
C	DA840
G	DOC873
B	MET9
B	ASP10
B	CYS11
B	PHE12
B	PHE13
B	SER42
B	THR43
B	SER55

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 402

Chain	Residue
B	ASP8
B	MET9
B	ASP103
B	GLU104
B	DCP401

---

site_id	AC3
Number of Residues	22
Details	BINDING SITE FOR RESIDUE DCP A 401

Chain	Residue
A	ASP8
A	MET9
A	ASP10
A	CYS11
A	PHE12
A	PHE13
A	SER42
A	THR43
A	ARG49
A	ASP103
A	GLU104
A	LYS157
A	MG402
A	HOH507
A	HOH514
A	HOH523
A	HOH547
A	HOH548
F	DA840
F	DG841
H	DOC873
H	HOH905

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 402

Chain	Residue
A	ASP8
A	MET9
A	ASP103
A	DCP401

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000250

Chain	Residue	Details
B	GLU104
A	GLU104

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
B	ASP8
B	ASP103
A	ASP8
A	ASP103

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Substrate discrimination => ECO:0000250

Chain	Residue	Details
B	PHE13
A	PHE13

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