4IRC

Polymerase-DNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0000731	biological_process	DNA synthesis involved in DNA repair
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006259	biological_process	DNA metabolic process
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0008296	molecular_function	3'-5'-DNA exonuclease activity
A	0009432	biological_process	SOS response
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
A	0070987	biological_process	error-free translesion synthesis
F	0000287	molecular_function	magnesium ion binding
F	0000731	biological_process	DNA synthesis involved in DNA repair
F	0003677	molecular_function	DNA binding
F	0003684	molecular_function	damaged DNA binding
F	0003887	molecular_function	DNA-directed DNA polymerase activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0006259	biological_process	DNA metabolic process
F	0006260	biological_process	DNA replication
F	0006261	biological_process	DNA-templated DNA replication
F	0006281	biological_process	DNA repair
F	0006974	biological_process	DNA damage response
F	0008296	molecular_function	3'-5'-DNA exonuclease activity
F	0009432	biological_process	SOS response
F	0016740	molecular_function	transferase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0034061	molecular_function	DNA polymerase activity
F	0042276	biological_process	error-prone translesion synthesis
F	0046872	molecular_function	metal ion binding
F	0070987	biological_process	error-free translesion synthesis

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE 0KX F 401

Chain	Residue
F	ASP8
F	ASP103
F	LYS157
F	MG402
F	MG403
F	HOH502
F	HOH514
F	HOH518
F	HOH536
G	DG840
H	DC873
F	MET9
F	ASP10
F	CYS11
F	PHE12
F	PHE13
F	SER42
F	THR43
F	ARG49

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 402

Chain	Residue
F	ASP8
F	MET9
F	ASP103
F	0KX401
F	MG403
F	HOH502

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG F 403

Chain	Residue
F	ASP8
F	ASP103
F	GLU104
F	0KX401
F	MG402
F	HOH502
F	HOH518

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE 0KX A 401

Chain	Residue
A	ASP8
A	MET9
A	ASP10
A	CYS11
A	PHE12
A	PHE13
A	SER42
A	THR43
A	ARG49
A	ASP103
A	LYS157
A	MG402
A	MG403
A	HOH516
A	HOH517
B	DG840
C	DC873

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 402

Chain	Residue
A	ASP8
A	MET9
A	ASP103
A	0KX401
A	MG403

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 403

Chain	Residue
A	ASP8
A	ASP103
A	GLU104
A	0KX401
A	MG402

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	362
Details	Domain: {"description":"UmuC"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Substrate discrimination","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---