Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004329 | molecular_function | formate-tetrahydrofolate ligase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006730 | biological_process | one-carbon metabolic process |
A | 0016874 | molecular_function | ligase activity |
A | 0035999 | biological_process | tetrahydrofolate interconversion |
B | 0004329 | molecular_function | formate-tetrahydrofolate ligase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006730 | biological_process | one-carbon metabolic process |
B | 0016874 | molecular_function | ligase activity |
B | 0035999 | biological_process | tetrahydrofolate interconversion |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 601 |
Chain | Residue |
A | LYS74 |
A | ARG97 |
A | GLY303 |
A | PHE304 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 602 |
Chain | Residue |
A | GLU34 |
A | SER44 |
A | LYS256 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 603 |
Chain | Residue |
A | MET533 |
A | GLY537 |
A | ARG175 |
A | ARG178 |
site_id | AC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 604 |
Chain | Residue |
A | SER446 |
A | LYS448 |
A | ARG507 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 605 |
Chain | Residue |
A | LYS448 |
A | ARG507 |
A | HOH788 |
A | HOH789 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE TOE A 606 |
Chain | Residue |
A | ARG162 |
A | ILE164 |
A | HOH803 |
site_id | AC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE TOE A 607 |
Chain | Residue |
A | ARG224 |
A | GLY481 |
A | TYR482 |
site_id | AC8 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE FOL A 608 |
Chain | Residue |
A | ALA383 |
A | PHE384 |
A | PRO385 |
A | GLU389 |
A | LEU392 |
A | TYR396 |
A | LEU408 |
A | TRP412 |
A | GLU417 |
A | HOH709 |
site_id | AC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE TOE B 600 |
Chain | Residue |
B | ARG162 |
B | ILE164 |
B | GLU194 |
site_id | BC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 601 |
Chain | Residue |
A | ALA188 |
B | ARG175 |
B | ARG178 |
B | MET533 |
B | GLY537 |
site_id | BC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 B 602 |
Chain | Residue |
B | LYS74 |
B | ARG97 |
B | GLY303 |
B | PHE304 |
Functional Information from PROSITE/UniProt
site_id | PS00721 |
Number of Residues | 11 |
Details | FTHFS_1 Formate--tetrahydrofolate ligase signature 1. GIKGGAAGGGY |
Chain | Residue | Details |
A | GLY106-TYR116 | |
site_id | PS00722 |
Number of Residues | 12 |
Details | FTHFS_2 Formate--tetrahydrofolate ligase signature 2. VATVRALKmHGG |
Chain | Residue | Details |
A | VAL331-GLY342 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | THR68 | |
B | THR68 | |