Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM A 801 |
| Chain | Residue |
| A | TRP409 |
| A | ARG596 |
| A | PHE704 |
| A | TYR706 |
| A | H4B802 |
| A | 1ET803 |
| A | ACT804 |
| A | HOH906 |
| A | HOH939 |
| A | CYS415 |
| A | VAL416 |
| A | SER457 |
| A | PHE584 |
| A | SER585 |
| A | TRP587 |
| A | MET589 |
| A | GLU592 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE H4B A 802 |
| Chain | Residue |
| A | SER334 |
| A | MET336 |
| A | VAL677 |
| A | TRP678 |
| A | HEM801 |
| A | CL807 |
| A | HOH919 |
| A | HOH1036 |
| B | TRP676 |
| B | PHE691 |
| B | HIS692 |
| B | GLN693 |
| B | GLU694 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 1ET A 803 |
| Chain | Residue |
| A | MET336 |
| A | LEU337 |
| A | GLN478 |
| A | ARG481 |
| A | PHE584 |
| A | GLY586 |
| A | TRP587 |
| A | GLU592 |
| A | ARG596 |
| A | ASP597 |
| A | ARG603 |
| A | TYR706 |
| A | HEM801 |
| A | CL808 |
| A | HOH906 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 804 |
| Chain | Residue |
| A | TRP587 |
| A | VAL649 |
| A | HEM801 |
| A | HOH989 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 805 |
| Chain | Residue |
| A | CYS326 |
| A | CYS331 |
| B | CYS326 |
| B | CYS331 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 806 |
| Chain | Residue |
| A | ARG596 |
| A | ASP600 |
| A | CL807 |
| A | HOH901 |
| B | HIS692 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 807 |
| Chain | Residue |
| A | ARG596 |
| A | ASP600 |
| A | H4B802 |
| A | ZN806 |
| A | HOH981 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 808 |
| Chain | Residue |
| A | GLN478 |
| A | TYR588 |
| A | ARG596 |
| A | ASP597 |
| A | 1ET803 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE H4B A 809 |
| Chain | Residue |
| A | TRP676 |
| A | PHE691 |
| A | HIS692 |
| A | GLN693 |
| A | GLU694 |
| A | HOH1032 |
| A | HOH1047 |
| B | SER334 |
| B | VAL677 |
| B | TRP678 |
| B | HEM801 |
| B | CL805 |
| B | HOH962 |
| site_id | BC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM B 801 |
| Chain | Residue |
| A | H4B809 |
| B | TRP409 |
| B | CYS415 |
| B | SER457 |
| B | PHE584 |
| B | SER585 |
| B | TRP587 |
| B | GLU592 |
| B | ARG596 |
| B | TRP678 |
| B | PHE704 |
| B | TYR706 |
| B | 1ET802 |
| site_id | BC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 1ET B 802 |
| Chain | Residue |
| B | TYR588 |
| B | GLU592 |
| B | ARG596 |
| B | ASP597 |
| B | ARG603 |
| B | TRP678 |
| B | HEM801 |
| B | CL806 |
| B | MET336 |
| B | LEU337 |
| B | GLN478 |
| B | ARG481 |
| B | TRP587 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 803 |
| Chain | Residue |
| B | TRP587 |
| B | HOH932 |
| B | HOH964 |
| B | HOH1020 |
| B | HOH1080 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 804 |
| Chain | Residue |
| A | HIS692 |
| B | ASP600 |
| B | CL805 |
| B | HOH901 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 805 |
| Chain | Residue |
| A | H4B809 |
| A | HOH978 |
| B | ARG596 |
| B | ASP600 |
| B | ZN804 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 806 |
| Chain | Residue |
| B | GLN478 |
| B | TYR588 |
| B | ARG596 |
| B | ASP597 |
| B | 1ET802 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P29475","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P29475","evidenceCode":"ECO:0000250"}]} |
