4IIV
Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Escherichia coli strain CFT073 complexed with NADP+ at 2.5 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016597 | molecular_function | amino acid binding |
| D | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAP A 1901 |
| Chain | Residue |
| A | GLY9 |
| A | PHE59 |
| A | ASP60 |
| A | VAL61 |
| A | ASN87 |
| A | ALA88 |
| A | GLY89 |
| A | ILE90 |
| A | THR110 |
| A | SER139 |
| A | TYR153 |
| A | SER11 |
| A | LYS157 |
| A | PRO183 |
| A | GLY184 |
| A | ILE186 |
| A | THR188 |
| A | MET190 |
| A | ILE191 |
| A | HOH2032 |
| A | HOH2033 |
| A | HOH2064 |
| A | LYS12 |
| A | HOH2066 |
| A | GLY13 |
| A | ILE14 |
| A | HIS32 |
| A | HIS34 |
| A | ARG35 |
| A | ASP36 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NAP B 3901 |
| Chain | Residue |
| B | GLY9 |
| B | SER11 |
| B | LYS12 |
| B | GLY13 |
| B | ILE14 |
| B | HIS34 |
| B | ARG35 |
| B | ASP36 |
| B | ASP60 |
| B | VAL61 |
| B | ASN87 |
| B | ALA88 |
| B | GLY89 |
| B | ILE90 |
| B | SER139 |
| B | SER140 |
| B | TYR153 |
| B | LYS157 |
| B | PRO183 |
| B | GLY184 |
| B | LEU185 |
| B | ILE186 |
| B | THR188 |
| B | HOH4033 |
| B | HOH4044 |
| B | HOH4046 |
| site_id | AC3 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP C 2901 |
| Chain | Residue |
| C | GLY9 |
| C | SER11 |
| C | LYS12 |
| C | GLY13 |
| C | ILE14 |
| C | HIS32 |
| C | HIS34 |
| C | ARG35 |
| C | ASP36 |
| C | PHE59 |
| C | ASP60 |
| C | VAL61 |
| C | ASN87 |
| C | ALA88 |
| C | GLY89 |
| C | ILE90 |
| C | SER139 |
| C | SER140 |
| C | TYR153 |
| C | LYS157 |
| C | PRO183 |
| C | GLY184 |
| C | ILE186 |
| C | THR188 |
| C | MET190 |
| C | ILE191 |
| C | HOH3007 |
| C | HOH3019 |
| site_id | AC4 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAP D 4901 |
| Chain | Residue |
| D | GLY89 |
| D | ILE90 |
| D | SER139 |
| D | TYR153 |
| D | LYS157 |
| D | PRO183 |
| D | GLY184 |
| D | ILE186 |
| D | THR188 |
| D | MET190 |
| D | HOH5059 |
| D | HOH5061 |
| D | HOH5064 |
| D | HOH5079 |
| D | GLY9 |
| D | SER11 |
| D | LYS12 |
| D | GLY13 |
| D | ILE14 |
| D | HIS32 |
| D | TYR33 |
| D | HIS34 |
| D | ARG35 |
| D | ASP36 |
| D | PHE59 |
| D | ASP60 |
| D | VAL61 |
| D | ASN87 |
| D | ALA88 |
