4II9

Crystal structure of Weissella viridescens FemXVv non-ribosomal amino acid transferase in complex with a peptidyl-RNA conjugate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008360	biological_process	regulation of cell shape
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016746	molecular_function	acyltransferase activity
A	0016755	molecular_function	aminoacyltransferase activity
A	0044038	biological_process	cell wall macromolecule biosynthetic process
A	0047206	molecular_function	UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity
A	0071555	biological_process	cell wall organization

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:14962386

Chain	Residue	Details
A	LYS36
A	TYR103
A	ARG211
A	TYR215
A	TYR256

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Important for catalytic activity => ECO:0000303|PubMed:12679335

Chain	Residue	Details
A	ASP108
A	GLU319

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 781

Chain	Residue	Details
A	LYS36	hydrogen bond donor, steric role
A	ASP108	proton acceptor
A	ARG211	hydrogen bond donor, steric role
A	PHE304	pi-pi interaction, van der waals interaction
A	LYS305	electrostatic stabiliser, hydrogen bond donor
A	GLU319	hydrogen bond donor, proton acceptor, proton donor

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