4IF8

Structure Of Vaspin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004867	molecular_function	serine-type endopeptidase inhibitor activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0006094	biological_process	gluconeogenesis
A	0008610	biological_process	lipid biosynthetic process
A	0010466	biological_process	negative regulation of peptidase activity
A	0043491	biological_process	phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0045721	biological_process	negative regulation of gluconeogenesis
A	0046628	biological_process	positive regulation of insulin receptor signaling pathway
A	0051055	biological_process	negative regulation of lipid biosynthetic process
A	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0090181	biological_process	regulation of cholesterol metabolic process
A	0090207	biological_process	regulation of triglyceride metabolic process
A	0140678	molecular_function	molecular function inhibitor activity
B	0004867	molecular_function	serine-type endopeptidase inhibitor activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005886	cellular_component	plasma membrane
B	0006094	biological_process	gluconeogenesis
B	0008610	biological_process	lipid biosynthetic process
B	0010466	biological_process	negative regulation of peptidase activity
B	0043491	biological_process	phosphatidylinositol 3-kinase/protein kinase B signal transduction
B	0045721	biological_process	negative regulation of gluconeogenesis
B	0046628	biological_process	positive regulation of insulin receptor signaling pathway
B	0051055	biological_process	negative regulation of lipid biosynthetic process
B	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B	0090181	biological_process	regulation of cholesterol metabolic process
B	0090207	biological_process	regulation of triglyceride metabolic process
B	0140678	molecular_function	molecular function inhibitor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 501

Chain	Residue
A	ARG211
A	LYS359
A	ARG363
A	HOH755
A	HOH789

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 501

Chain	Residue
B	LYS320
B	HIS344
B	ARG345
B	SER346

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Cleavage => ECO:0000269|PubMed:26529565

Chain	Residue	Details
A	MET378
B	MET378

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:28668641

Chain	Residue	Details
A	ASN221
A	ASN233
B	ASN221
B	ASN233

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine => ECO:0000269|PubMed:28668641

Chain	Residue	Details
A	ASN267
B	ASN267

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