4I27
Ternary complex of mouse TdT with ssDNA and incoming nucleotide
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | ASP343 |
| A | ASP345 |
| A | D3T602 |
| A | HOH897 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE D3T A 602 |
| Chain | Residue |
| A | HIS342 |
| A | ASP343 |
| A | ASP345 |
| A | GLY449 |
| A | TRP450 |
| A | GLY452 |
| A | MG601 |
| A | HOH750 |
| A | HOH865 |
| C | 2DT6 |
| A | GLY332 |
| A | GLY333 |
| A | ARG336 |
| A | LYS338 |
| A | GLY341 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 603 |
| Chain | Residue |
| A | THR253 |
| A | VAL255 |
| A | VAL258 |
| C | DA5 |
Functional Information from PROSITE/UniProt
| site_id | PS00522 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_X DNA polymerase family X signature. GGFrRGkmtGhDVDFLItsP |
| Chain | Residue | Details |
| A | GLY332-PRO351 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Region: {"description":"Involved in DNA binding","evidences":[{"source":"PubMed","id":"11823435","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23856622","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4I2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4I2C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4I2D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4I2E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1JMS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4I2B","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 632 |
| Chain | Residue | Details |
| A | ASP343 | metal ligand |
| A | ASP345 | metal ligand |
| A | ASP434 | metal ligand, proton acceptor, proton donor |
