Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 501 |
Chain | Residue |
A | GLU316 |
A | ASP451 |
A | HIS457 |
A | HIS459 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 502 |
Chain | Residue |
A | ASP192 |
A | HIS458 |
A | HIS460 |
A | HOH769 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 503 |
Chain | Residue |
A | HIS110 |
A | HIS150 |
A | HOH755 |
A | GLU78 |
site_id | AC4 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE 1CH A 504 |
Chain | Residue |
A | GLY72 |
A | GLN73 |
A | GLY74 |
A | LEU91 |
A | TYR132 |
A | GLY291 |
A | THR292 |
A | THR293 |
A | HOH850 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
Chain | Residue | Details |
A | ILE90-VAL101 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP93 | |
A | ASP289 | |
Chain | Residue | Details |
A | LYS126 | |
A | LYS275 | |
A | LYS279 | |
A | LYS285 | |
A | LYS299 | |
A | LYS300 | |
A | LYS307 | |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN153 | |
A | ASN172 | |
A | ASN223 | |
A | ASN354 | |