4HYO

Crystal Structure of MthK Pore

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE K A 201

Chain	Residue
A	GLY61
A	TYR62
A	K202
B	GLY61
B	TYR62
C	GLY61
C	TYR62
D	GLY61
D	TYR62

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE K A 202

Chain	Residue
A	VAL60
A	GLY61
A	K201
A	K203
B	VAL60
B	GLY61
C	VAL60
C	GLY61
D	VAL60
D	GLY61

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE K A 203

Chain	Residue
A	THR59
A	VAL60
A	K202
A	K204
B	THR59
B	VAL60
C	THR59
C	VAL60
D	THR59
D	VAL60

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K A 204

Chain	Residue
A	THR59
A	K203
B	THR59
C	THR59
D	THR59

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE HEZ A 205

Chain	Residue
A	ALA29
A	TYR33
F	ALA29
F	TYR33

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HEZ A 206

Chain	Residue
A	ARG22

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HEZ B 201

Chain	Residue
B	ALA29
E	ALA29

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HEZ B 202

Chain	Residue
B	ARG22

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE HEZ C 201

Chain	Residue
C	ALA29
C	HOH323
G	ALA29

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HEZ C 202

Chain	Residue
C	ARG22

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE HEZ D 201

Chain	Residue
D	ALA29
D	HOH318
H	ALA29
H	ILE32

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE HEZ D 202

Chain	Residue
D	ARG22
H	ILE32
H	TRP46

---

site_id	BC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE K E 201

Chain	Residue
E	GLY61
E	TYR62
E	K202
F	GLY61
F	TYR62
G	GLY61
G	TYR62
H	GLY61
H	TYR62

---

site_id	BC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE K E 202

Chain	Residue
E	VAL60
E	GLY61
E	K201
E	K203
F	VAL60
F	GLY61
G	VAL60
G	GLY61
H	VAL60
H	GLY61

---

site_id	BC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE K E 203

Chain	Residue
E	THR59
E	VAL60
E	K202
E	K204
F	THR59
F	VAL60
G	THR59
G	VAL60
H	THR59
H	VAL60

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K E 204

Chain	Residue
E	THR59
E	K203
F	THR59
G	THR59
H	THR59

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HEZ E 205

Chain	Residue
E	ARG22
E	ALA29

---

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HEZ F 201

Chain	Residue
F	ARG22
F	ALA29

---

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HEZ G 201

Chain	Residue
G	ARG22
G	LEU26

---

site_id	CC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HEZ H 201

Chain	Residue
H	ARG22

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	160
Details	Transmembrane: {"description":"Helical; Name=Outer helix M1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	80
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	72
Details	Intramembrane: {"description":"Helical; Pore-forming","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	40
Details	Intramembrane: {"description":"Pore-forming","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	200
Details	Transmembrane: {"description":"Helical; Name=Inner helix M2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	40
Details	Motif: {"description":"Selectivity filter"}

Chain

Residue

Details

---