Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004089 | molecular_function | carbonate dehydratase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004089 | molecular_function | carbonate dehydratase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0004089 | molecular_function | carbonate dehydratase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0004089 | molecular_function | carbonate dehydratase activity |
| D | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 301 |
| Chain | Residue |
| A | HIS91 |
| A | HIS93 |
| A | HIS117 |
| A | V50302 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE V50 A 302 |
| Chain | Residue |
| A | SER130 |
| A | LEU139 |
| A | VAL141 |
| A | LEU197 |
| A | THR198 |
| A | THR199 |
| A | PRO200 |
| A | ASN203 |
| A | TRP208 |
| A | ZN301 |
| A | PEG303 |
| A | EDO304 |
| A | HOH543 |
| A | HOH592 |
| A | HOH604 |
| A | GLN89 |
| A | HIS91 |
| A | HIS93 |
| A | HIS117 |
| A | VAL119 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 303 |
| Chain | Residue |
| A | ASN64 |
| A | LYS69 |
| A | GLN89 |
| A | THR199 |
| A | V50302 |
| A | EDO304 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 304 |
| Chain | Residue |
| A | ASN64 |
| A | SER67 |
| A | GLN89 |
| A | HIS91 |
| A | HIS93 |
| A | THR199 |
| A | V50302 |
| A | PEG303 |
| A | HOH498 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 305 |
| Chain | Residue |
| A | SER42 |
| A | LEU43 |
| A | THR44 |
| A | GLY80 |
| A | TYR190 |
| A | ARG192 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 306 |
| Chain | Residue |
| A | ASP40 |
| A | TYR258 |
| A | HOH488 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 301 |
| Chain | Residue |
| B | HIS91 |
| B | HIS93 |
| B | HIS117 |
| B | V50302 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE V50 B 302 |
| Chain | Residue |
| B | GLN89 |
| B | HIS91 |
| B | HIS93 |
| B | HIS117 |
| B | VAL119 |
| B | SER133 |
| B | LEU197 |
| B | THR198 |
| B | THR199 |
| B | PRO200 |
| B | ZN301 |
| B | EDO304 |
| B | EDO305 |
| B | HOH492 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG B 303 |
| Chain | Residue |
| B | HIS164 |
| B | PHE173 |
| B | HOH499 |
| B | HOH573 |
| B | HOH769 |
| C | GLN58 |
| C | HIS161 |
| C | PHE173 |
| C | PRO175 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 304 |
| Chain | Residue |
| B | ASN64 |
| B | HIS66 |
| B | GLN89 |
| B | HIS91 |
| B | V50302 |
| B | EDO305 |
| B | HOH450 |
| B | HOH642 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 305 |
| Chain | Residue |
| B | ASN64 |
| B | LYS69 |
| B | V50302 |
| B | EDO304 |
| B | HOH641 |
| B | HOH648 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 306 |
| Chain | Residue |
| B | ASN71 |
| B | LEU72 |
| B | THR88 |
| B | HOH437 |
| B | HOH445 |
| B | HOH456 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 307 |
| Chain | Residue |
| B | SER83 |
| B | ASP124 |
| B | MET234 |
| B | ASP235 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 308 |
| Chain | Residue |
| B | LYS57 |
| B | GLN58 |
| B | HOH617 |
| C | HIS164 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 301 |
| Chain | Residue |
| C | HIS91 |
| C | HIS93 |
| C | HIS117 |
| C | V50302 |
| site_id | BC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE V50 C 302 |
| Chain | Residue |
| C | GLN89 |
| C | HIS91 |
| C | HIS93 |
| C | HIS117 |
| C | VAL119 |
| C | SER133 |
| C | LEU139 |
| C | LEU197 |
| C | THR198 |
| C | THR199 |
| C | PRO200 |
| C | PRO201 |
| C | TRP208 |
| C | ZN301 |
| C | EDO303 |
| C | HOH608 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 303 |
| Chain | Residue |
| C | ASN64 |
| C | HIS66 |
| C | GLN89 |
| C | HIS91 |
| C | V50302 |
| C | HOH609 |
| C | HOH611 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 301 |
| Chain | Residue |
| D | HIS91 |
| D | HIS93 |
| D | HIS117 |
| D | V50302 |
| site_id | CC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE V50 D 302 |
| Chain | Residue |
| D | GLN89 |
| D | HIS91 |
| D | HIS93 |
| D | HIS117 |
| D | VAL119 |
| D | SER133 |
| D | LEU197 |
| D | THR198 |
| D | THR199 |
| D | PRO200 |
| D | ZN301 |
| D | EDO304 |
| D | EDO305 |
| D | HOH662 |
| site_id | CC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG D 303 |
| Chain | Residue |
| D | GLN163 |
| D | GLU220 |
| D | ALA224 |
| D | HOH531 |
| D | HOH551 |
| D | HOH582 |
| D | HOH606 |
| D | HOH626 |
| D | HOH786 |
| site_id | CC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 304 |
| Chain | Residue |
| D | ASN64 |
| D | HIS66 |
| D | SER67 |
| D | GLN89 |
| D | HIS91 |
| D | V50302 |
| D | EDO305 |
| D | HOH664 |
| site_id | CC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 305 |
| Chain | Residue |
| D | ASN64 |
| D | LYS69 |
| D | GLN89 |
| D | V50302 |
| D | EDO304 |
| D | HOH663 |
| D | HOH665 |
| site_id | CC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 306 |
| Chain | Residue |
| A | ALA55 |
| A | PRO175 |
| A | HOH677 |
| A | HOH728 |
| A | HOH729 |
| D | SER160 |
| D | HIS161 |
| D | HIS164 |
Functional Information from PROSITE/UniProt
| site_id | PS00162 |
| Number of Residues | 17 |
| Details | ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVsgqhFaaELHIV |
| Chain | Residue | Details |
| A | SER103-VAL119 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS66 | |
| B | HIS66 | |
| C | HIS66 | |
| D | HIS66 | |
| Chain | Residue | Details |
| A | HIS91 | |
| D | HIS91 | |
| D | HIS93 | |
| D | HIS117 | |
| A | HIS93 | |
| A | HIS117 | |
| B | HIS91 | |
| B | HIS93 | |
| B | HIS117 | |
| C | HIS91 | |
| C | HIS93 | |
| C | HIS117 | |
| Chain | Residue | Details |
| A | THR198 | |
| B | THR198 | |
| C | THR198 | |
| D | THR198 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN52 | |
| A | ASN134 | |
| B | ASN52 | |
| B | ASN134 | |
| C | ASN52 | |
| C | ASN134 | |
| D | ASN52 | |
| D | ASN134 | |
