4HHO

Serum paraoxonase-1 by directed evolution with the H115W mutation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004064	molecular_function	arylesterase activity
A	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
A	ASP54
A	ILE117
A	ASP169
A	HOH573
A	HOH615
A	HOH616

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 402

Chain	Residue
A	HOH598
A	HOH599
A	HOH600
A	GLU53
A	ASP269
A	HOH596

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LMT A 403

Chain	Residue
A	GLN20
A	LEU198
A	LEU200
A	TRP202

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR A 404

Chain	Residue
A	ASN287
A	ARG290
A	GLY301
A	HOH574

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 405

Chain	Residue
A	ILE187
A	ASP188

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