Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4HHM

Crystal structure of a mutant, G219A, of Glucose Isomerase from Streptomyces sp. SK

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0009045	molecular_function	xylose isomerase activity
A	0016853	molecular_function	isomerase activity
A	0042732	biological_process	D-xylose metabolic process
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0009045	molecular_function	xylose isomerase activity
B	0016853	molecular_function	isomerase activity
B	0042732	biological_process	D-xylose metabolic process
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0009045	molecular_function	xylose isomerase activity
C	0016853	molecular_function	isomerase activity
C	0042732	biological_process	D-xylose metabolic process
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0009045	molecular_function	xylose isomerase activity
D	0016853	molecular_function	isomerase activity
D	0042732	biological_process	D-xylose metabolic process
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0005737	cellular_component	cytoplasm
E	0005975	biological_process	carbohydrate metabolic process
E	0009045	molecular_function	xylose isomerase activity
E	0016853	molecular_function	isomerase activity
E	0042732	biological_process	D-xylose metabolic process
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0005737	cellular_component	cytoplasm
F	0005975	biological_process	carbohydrate metabolic process
F	0009045	molecular_function	xylose isomerase activity
F	0016853	molecular_function	isomerase activity
F	0042732	biological_process	D-xylose metabolic process
F	0046872	molecular_function	metal ion binding
G	0000287	molecular_function	magnesium ion binding
G	0005737	cellular_component	cytoplasm
G	0005975	biological_process	carbohydrate metabolic process
G	0009045	molecular_function	xylose isomerase activity
G	0016853	molecular_function	isomerase activity
G	0042732	biological_process	D-xylose metabolic process
G	0046872	molecular_function	metal ion binding
H	0000287	molecular_function	magnesium ion binding
H	0005737	cellular_component	cytoplasm
H	0005975	biological_process	carbohydrate metabolic process
H	0009045	molecular_function	xylose isomerase activity
H	0016853	molecular_function	isomerase activity
H	0042732	biological_process	D-xylose metabolic process
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO A 2001

Chain	Residue
A	GLU217
A	HIS220
A	ASP255
A	ASP257

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 2002

Chain	Residue
A	HOH2260
A	GLU181
A	GLU217
A	ASP245
A	ASP287
A	HOH2259

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO B 2001

Chain	Residue
B	GLU217
B	HIS220
B	ASP255
B	ASP257
B	HOH2251

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG B 2002

Chain	Residue
B	GLU181
B	GLU217
B	HIS220
B	ASP245
B	ASP287
B	HOH2161
B	HOH2337

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO C 2001

Chain	Residue
C	GLU217
C	HIS220
C	ASP255
C	ASP257

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 2002

Chain	Residue
C	GLU181
C	GLU217
C	ASP245
C	ASP287
C	HOH2313
C	HOH2314

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO D 2001

Chain	Residue
D	GLU217
D	HIS220
D	ASP255
D	ASP257

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 2002

Chain	Residue
D	GLU181
D	GLU217
D	ASP245
D	ASP287
D	HOH2254

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO E 2001

Chain	Residue
E	GLU217
E	HIS220
E	ASP255
E	ASP257
E	HOH2359

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG E 2002

Chain	Residue
E	GLU181
E	GLU217
E	ASP245
E	ASP287
E	HOH2151
E	HOH2261

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO F 2001

Chain	Residue
F	GLU217
F	HIS220
F	ASP255
F	ASP257

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 2002

Chain	Residue
F	GLU181
F	GLU217
F	ASP245
F	ASP287
F	HOH2141
F	HOH2210

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO G 2001

Chain	Residue
G	GLU217
G	HIS220
G	ASP255
G	ASP257

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG G 2002

Chain	Residue
G	GLU181
G	GLU217
G	ASP245
G	ASP287
G	HOH2261
G	HOH2262

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO H 2001

Chain	Residue
H	GLU217
H	HIS220
H	ASP255
H	ASP257
H	HOH2387

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG H 2002

Chain	Residue
H	GLU181
H	GLU217
H	ASP245
H	ASP287
H	HOH2276
H	HOH2387

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)