4HHH

Structure of Pisum sativum Rubisco

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004497	molecular_function	monooxygenase activity
A	0009507	cellular_component	chloroplast
A	0009853	biological_process	photorespiration
A	0015977	biological_process	carbon fixation
A	0015979	biological_process	photosynthesis
A	0016829	molecular_function	lyase activity
A	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
A	0019253	biological_process	reductive pentose-phosphate cycle
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0004497	molecular_function	monooxygenase activity
B	0009507	cellular_component	chloroplast
B	0009853	biological_process	photorespiration
B	0015977	biological_process	carbon fixation
B	0015979	biological_process	photosynthesis
B	0016829	molecular_function	lyase activity
B	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
B	0019253	biological_process	reductive pentose-phosphate cycle
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004497	molecular_function	monooxygenase activity
C	0009507	cellular_component	chloroplast
C	0009853	biological_process	photorespiration
C	0015977	biological_process	carbon fixation
C	0015979	biological_process	photosynthesis
C	0016829	molecular_function	lyase activity
C	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
C	0019253	biological_process	reductive pentose-phosphate cycle
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0004497	molecular_function	monooxygenase activity
D	0009507	cellular_component	chloroplast
D	0009853	biological_process	photorespiration
D	0015977	biological_process	carbon fixation
D	0015979	biological_process	photosynthesis
D	0016829	molecular_function	lyase activity
D	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
D	0019253	biological_process	reductive pentose-phosphate cycle
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE RUB A 501

Chain	Residue
A	THR173
A	SER379
A	GLY380
A	GLY381
A	GLY403
A	GLY404
A	HOH622
A	HOH634
A	HOH661
A	HOH662
A	HOH682
A	LYS177
B	THR65
B	TRP66
B	ASN123
B	HOH716
A	ASP203
A	GLU204
A	HIS294
A	ARG295
A	HIS327
A	LYS334
A	LEU335

---

site_id	AC2
Number of Residues	22
Details	BINDING SITE FOR RESIDUE RUB B 501

Chain	Residue
A	THR65
A	TRP66
A	ASN123
B	LYS175
B	ASP203
B	GLU204
B	HIS294
B	ARG295
B	HIS327
B	LYS334
B	LEU335
B	SER379
B	GLY380
B	GLY381
B	GLY403
B	GLY404
B	HOH611
B	HOH638
B	HOH682
B	HOH684
B	HOH691
B	HOH728

---

site_id	AC3
Number of Residues	22
Details	BINDING SITE FOR RESIDUE RUB C 501

Chain	Residue
C	THR173
C	LYS175
C	ASP203
C	GLU204
C	HIS294
C	ARG295
C	HIS327
C	LEU335
C	SER379
C	GLY380
C	GLY381
C	GLY403
C	GLY404
C	HOH614
C	HOH651
C	HOH652
C	HOH675
C	HOH703
C	HOH737
D	THR65
D	TRP66
D	ASN123

---

site_id	AC4
Number of Residues	20
Details	BINDING SITE FOR RESIDUE RUB D 501

Chain	Residue
C	THR65
C	TRP66
C	ASN123
D	LYS175
D	LYS177
D	ASP203
D	GLU204
D	ARG295
D	HIS327
D	LYS334
D	LEU335
D	SER379
D	GLY381
D	GLY403
D	GLY404
D	HOH709
D	HOH717
D	HOH719
D	HOH720
D	HOH745

---

Functional Information from PROSITE/UniProt

site_id	PS00157
Number of Residues	9
Details	RUBISCO_LARGE Ribulose bisphosphate carboxylase large chain active site. GlDFtKdDE

Chain	Residue	Details
A	GLY196-GLU204

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
A	LYS175
A	HIS294
B	LYS175
B	HIS294
C	LYS175
C	HIS294
D	LYS175
D	HIS294

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	BINDING: BINDING => ECO:0000269|PubMed:26197050, ECO:0007744|PDB:4MKV

Chain	Residue	Details
A	LYS175
B	LYS175
B	LYS177
B	ARG295
B	HIS327
B	LYS334
B	SER379
B	GLY381
B	GLY403
B	GLY404
C	LYS175
A	LYS177
C	LYS177
C	ARG295
C	HIS327
C	LYS334
C	SER379
C	GLY381
C	GLY403
C	GLY404
D	LYS175
D	LYS177
A	ARG295
D	ARG295
D	HIS327
D	LYS334
D	SER379
D	GLY381
D	GLY403
D	GLY404
A	HIS327
A	LYS334
A	SER379
A	GLY381
A	GLY403
A	GLY404

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: via carbamate group => ECO:0000250

Chain	Residue	Details
A	LYS201
B	LYS201
C	LYS201
D	LYS201

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP203
A	GLU204
B	ASP203
B	GLU204
C	ASP203
C	GLU204
D	ASP203
D	GLU204

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	SITE: Transition state stabilizer => ECO:0000250

Chain	Residue	Details
A	LYS334
B	LYS334
C	LYS334
D	LYS334

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	MOD_RES: N-acetylproline => ECO:0000269|PubMed:16668742

Chain	Residue	Details
A	PRO3
B	PRO3
C	PRO3
D	PRO3

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:16668742

Chain	Residue	Details
A	LYS14
B	LYS14
C	LYS14
D	LYS14

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	MOD_RES: N6-carboxylysine => ECO:0000250

Chain	Residue	Details
A	LYS201
B	LYS201
C	LYS201
D	LYS201

---