Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0007596 | biological_process | blood coagulation |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0006508 | biological_process | proteolysis |
| B | 0007596 | biological_process | blood coagulation |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0006508 | biological_process | proteolysis |
| C | 0007596 | biological_process | blood coagulation |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0006508 | biological_process | proteolysis |
| D | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 401 |
| Chain | Residue |
| B | TYR184 |
| B | ARG221 |
| B | LYS224 |
| B | HOH509 |
| B | HOH516 |
| B | HOH529 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA D 401 |
| Chain | Residue |
| D | ARG221 |
| D | LYS224 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 15U B 402 |
| Chain | Residue |
| B | TYR60 |
| B | TRP60 |
| B | LYS60 |
| B | ASN149 |
| B | ASP189 |
| B | ALA190 |
| B | GLU192 |
| B | SER214 |
| B | TRP215 |
| B | GLY216 |
| B | GLY219 |
| B | HIS57 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 15U D 402 |
| Chain | Residue |
| D | HIS57 |
| D | TYR60 |
| D | TRP60 |
| D | ASP189 |
| D | ALA190 |
| D | GLU192 |
| D | VAL213 |
| D | SER214 |
| D | TRP215 |
| D | GLY216 |
| D | GLY219 |
| D | GLY226 |
| D | HOH521 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| B | LEU53-CYS58 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| B | HIS57 | |
| B | ASP102 | |
| B | ALA195 | |
| D | HIS57 | |
| D | ASP102 | |
| D | ALA195 | |
| Chain | Residue | Details |
| B | ASN60 | |
| D | ASN60 | |
