Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0006508 | biological_process | proteolysis |
A | 0007596 | biological_process | blood coagulation |
B | 0004252 | molecular_function | serine-type endopeptidase activity |
B | 0005509 | molecular_function | calcium ion binding |
B | 0006508 | biological_process | proteolysis |
B | 0007596 | biological_process | blood coagulation |
C | 0004252 | molecular_function | serine-type endopeptidase activity |
C | 0005576 | cellular_component | extracellular region |
C | 0006508 | biological_process | proteolysis |
C | 0007596 | biological_process | blood coagulation |
D | 0004252 | molecular_function | serine-type endopeptidase activity |
D | 0005509 | molecular_function | calcium ion binding |
D | 0006508 | biological_process | proteolysis |
D | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA B 401 |
Chain | Residue |
B | TYR184 |
B | ARG221 |
B | LYS224 |
B | HOH509 |
B | HOH516 |
B | HOH529 |
site_id | AC2 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE NA D 401 |
Chain | Residue |
D | ARG221 |
D | LYS224 |
site_id | AC3 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE 15U B 402 |
Chain | Residue |
B | TYR60 |
B | TRP60 |
B | LYS60 |
B | ASN149 |
B | ASP189 |
B | ALA190 |
B | GLU192 |
B | SER214 |
B | TRP215 |
B | GLY216 |
B | GLY219 |
B | HIS57 |
site_id | AC4 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE 15U D 402 |
Chain | Residue |
D | HIS57 |
D | TYR60 |
D | TRP60 |
D | ASP189 |
D | ALA190 |
D | GLU192 |
D | VAL213 |
D | SER214 |
D | TRP215 |
D | GLY216 |
D | GLY219 |
D | GLY226 |
D | HOH521 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
B | LEU53-CYS58 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
B | HIS57 | |
B | ASP102 | |
B | ALA195 | |
D | HIS57 | |
D | ASP102 | |
D | ALA195 | |
Chain | Residue | Details |
B | ASN60 | |
D | ASN60 | |